Zinotinel Tablet 35 milligrams (Sodium Risedronate)

Adult dose

Adults: Administer 35 mg of risedronate sodium orally once weekly. In older adults (over 60 years of age), no dosage adjustment is necessary because the bioavailability and pharmacodynamics of this drug are similar to those in younger people. No dosage adjustment is necessary in patients with a creatinine clearance of 30 mL/min or greater. This drug is contraindicated in patients with severe renal impairment and a creatinine clearance below 30 mL/min.

Child dose

The safety and efficacy in children under 18 years of age have not been established.

This drug is an oral bisphosphonate that can irritate the upper gastrointestinal mucosa. Care should be taken especially in patients with Barrett's esophagus, dysphagia, esophageal disease, gastritis, duodenitis, ulcers, etc. When taking this medication, it should be swallowed with a sufficient amount of water (170-230 mL) and you must not lie down for at least 30 minutes after taking it. If symptoms such as dysphagia, pain behind the sternum, or heartburn occur after taking this medication, stop taking it immediately and consult a doctor. This medication should not be administered to patients with esophageal stricture, hypocalcemia, severe renal impairment, pregnant or breastfeeding women, and certain genetically intolerant lactose patients. Care must be taken when administering to patients with a history of Barrett's esophagus or allergies, and caution is also needed for those allergic to Yellow No. 5. When taking this medication, drugs or foods containing calcium, magnesium, iron, aluminum, etc. can interfere with absorption, so should be taken at a time interval. Rarely, serious side effects such as osteonecrosis of the jaw, atypical femoral fractures, and osteonecrosis of the external auditory canal may occur with long-term use, thus regular examinations and monitoring are necessary. Adequate calcium and vitamin D intake is important during the use of this drug, and maintaining a healthy lifestyle along with weight-bearing exercises is recommended. Women who are pregnant or may become pregnant and breastfeeding women should avoid taking this medication and consult a doctor if necessary. There is no difference in safety between elderly and young patients, but safety and efficacy have not been established in children under 18 years of age. Symptoms of hypocalcemia may occur in case of overdose, so calcium supplementation and gastric lavage may be needed in emergency situations. This drug should be stored out of reach of children and should not be transferred to other containers.

• esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• bleeding
• infection
• back pain
• accidental injury
• pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is recommended to store it at room temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the drug can be maintained for a long time.

Appearance

Pale orange round film-coated tablet

Package unit

4 tablets (4 tablets x 1 PTP)