Medication info

Centamin Injection (Fursultiamine Hydrochloride)

Prescription medicationInjections
Ingredient · strength
Fursultiamine Hydrochloride›5.46mg / 1mL
Manufacturer / importer
(주)넥스팜코리아
Appearance
A colorless to pale yellow transparent liquid in a brown transparent glass ampoule injection
Packaging
10mL/ampoule × 10, 10mL/ampoule × 50
Approval status
Active

MFDS item code 200713288 · Notified 2007.12.13

Summary

Main use
Improvement of neuropathy and cardiac disorders related to vitamin B1 deficiency and metabolic disorders
Who uses it
Adults
Adult dosage
As fursultiamine, usually 5 ~ 100 mg per day for adults is administered subcutaneously, intramuscularly, or intravenously. Adjustments should be made according to symptoms.

Ingredients

Manufacturer
(주)넥스팜코리아

Efficacy & effects

Improvement of neuropathy and cardiac disorders related to vitamin B1 deficiency and metabolic disorders

  • Vitamin B1 deficiency
  • debilitating diseases
  • hyperthyroidism
  • Wernicke’s encephalopathy
  • beriberi heart disease
  • neuropathy
  • myalgia
  • arthralgia
  • peripheral neuritis
  • peripheral nerve palsy
  • myocardial metabolic disorders
  • constipation
View approved original text

This medication is used for the prevention and treatment of vitamin B1 deficiency. It is especially used to supplement the increased need for vitamin B1 in cases of debilitating diseases, hyperthyroidism, during pregnancy or lactation, and due to intense physical labor. It also aids in the treatment of Wernicke’s encephalopathy and beriberi heart disease. Additionally, it is used when vitamin B1 deficiency or metabolic disorders are suspected, such as neuropathy, myalgia, and peripheral neuritis; however, it is important not to use it without purpose for more than one month. This medication improves various symptoms caused by vitamin B1 deficiency.

Dosage and Administration

Adult dosage

As fursultiamine, usually 5 ~ 100 mg per day for adults is administered subcutaneously, intramuscularly, or intravenously. Adjustments should be made according to symptoms.

Precautions

This medication is an injection in a glass ampoule, so care must be taken when opening the ampoule to avoid glass fragments mixing in. Special caution is required when administered to children and the elderly. It should not be used in patients who have had allergies to this medication or its components. Furthermore, it should be administered cautiously to patients who have previously experienced drug allergic reactions. When using this medication, serious side effects such as shock may occur rarely, so if symptoms such as blood pressure drop, chest pain, or difficulty breathing appear, administration should be stopped immediately and appropriate treatment should be received. In addition, rare side effects such as rashes, nausea, vomiting, oral inflammation, diarrhea, headaches, and frequent urination may occur, so if symptoms arise, administration should be stopped and a doctor should be consulted. When injecting, it can cause pain in the veins, so it should be injected as slowly as possible, and any remaining medication should not be reused to avoid bacterial contamination. When opening the ampoule, it should be held with the marked part facing upward and the opposite side should be carefully pressed to break it, and the upper part of the ampoule should be cleaned with alcohol cotton to prevent foreign substances from entering. This medication should be stored in a secure place out of the reach of children, and transferring it to other containers should be avoided as it can cause quality degradation or accidents.

Side effects and when to seek care immediately

Serious side effects

Low blood pressure, chest pain, difficulty breathing → possibility of shock

Mild side effects

  • Nausea
  • vomiting
  • glossitis
  • diarrhea
  • headache
  • frequent urination

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that can block light, and can be safely stored at room temperature between 1 degree and 30 degrees Celsius. Storing it this way can maintain the medication's effectiveness for a long time.

Appearance and packaging

Appearance

A colorless to pale yellow transparent liquid in a brown transparent glass ampoule injection

Package unit

10mL/ampoule × 10, 10mL/ampoule × 50

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.