Risnel Tablet 35 mg (Risedronate Sodium Hydrate)

Adult dose

1. Adults: Administer 35 mg of risedronate sodium orally once weekly. 2. Elderly patients: No dose adjustment is necessary in elderly patients (over 60 years of age), because the bioavailability and pharmacodynamics of this medicine are similar to those in younger people. 4. Patients with renal impairment: No dose adjustment is necessary for patients with a creatinine clearance of 30 mL/min or higher. This medicine is contraindicated in patients with severe renal impairment and a creatinine clearance below 30 mL/min. Because food interferes with the absorption of this medicine, take it at least 30 minutes before breakfast to ensure adequate absorption, or at least 2 hours apart from food or beverages at any time of day. Take this medicine in an upright position with a sufficient amount of plain water (170 ∼ 230 mL) to facilitate passage into the stomach and reduce the possibility of esophageal irritation. Taking this medicine with other beverages, including mineral water, may reduce its absorption. Do not chew or suck this medicine because of the possibility of oropharyngeal ulceration. Patients should not lie down for at least 30 minutes after taking it. If a patient forgets to take the medicine on the scheduled day, take it the next morning when remembered. Resume the usual dosing schedule on the next scheduled day. Do not take 2 tablets on the same day.

Child dose

Children under 18 years of age: Safety and efficacy have not been established.

This medication can irritate the gastric and esophageal mucosa; caution is advised for those with gastrointestinal diseases such as esophagitis or ulcers. If symptoms of esophageal abnormalities such as dysphagia, pain, or heartburn occur, stop taking the medication immediately and consult a physician. Take with a sufficient amount of water and do not lie down for at least 30 minutes after ingestion. It is crucial to adhere to the exact method of taking this medication to reduce the risk of serious side effects if the medication remains in the esophagus. This medication should not be administered to patients with certain diseases or conditions, such as esophageal stricture, hypocalcemia, severe renal impairment, pregnant women or those who may become pregnant, and individuals with lactose intolerance. Caution is advised for individuals with upper gastrointestinal disorders such as Barrett's esophagus, gastritis, or duodenitis. Various side effects like dyspepsia, abdominal pain, diarrhea, muscle pain, joint pain, headache, dizziness may occur, so consult a physician if unusual symptoms persist. The absorption of this medication may be hindered if taken with foods or medications containing calcium, magnesium, or iron, so it is best to maintain an interval of some time before and after taking this medication. Pregnant or breastfeeding women should avoid taking this medication or should make a decision after consulting a specialist. Safety has not been established for children; it is advisable not to use in individuals under 18 years of age. Overdose can lead to hypocalcemia, and treatment such as administering milk or calcium-containing antacids and gastric lavage may be necessary. Store this medication out of reach of children and do not transfer to another container for safety and quality reasons.

• esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• hemorrhage
• infection
• low back pain
• accidental injury
• pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain a room temperature between 1°C and 30°C.

Appearance

Orange rectangular film-coated tablet

Package unit

4 tablets (4 tablets/PTP packaging x 1)