Janumet Tablet 50/500 mg

Adult dose

This medication is generally taken twice daily with food, and the dosage should be gradually increased to reduce gastrointestinal adverse effects associated with metformin. 1. Patients not currently treated with metformin: Start with this medication 50/500 mg, taking one tablet twice daily, and can increase to 50/1000 mg, one tablet twice daily. 2. Patients currently being treated with metformin:

This medication is composed of sitagliptin and metformin and is used in the treatment of diabetes. The sitagliptin component can rarely cause severe allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, use should be discontinued immediately. Additionally, inflammation of the pancreas, known as pancreatitis, may occur, so if symptoms such as abdominal pain, nausea, or vomiting arise, immediate consultation with a doctor is necessary. The metformin component can cause a rare but serious metabolic disorder called lactic acidosis, and it should not be used in patients with poor kidney function or liver disease. Patients with reduced kidney function, serious infections, dehydration, heart failure, etc., should not be administered this medication, and it should be temporarily discontinued during certain periods before and after surgery. This medication is not administered to pregnant or breastfeeding women or children under 18 years of age as safety has not been established. During treatment with this medication, kidney function and blood tests, as well as vitamin B12 levels, should be monitored regularly. If sudden fatigue, muscle pain, difficulty breathing, or abdominal pain occur, a doctor should be informed immediately. The risk of hypoglycemia may increase when taken in conjunction with other medications that lower blood sugar, so attention should be paid to symptoms and medication dosage adjustments may be necessary. Alcohol consumption may elevate the risk of lactic acidosis, so drinking should be avoided while taking this medication. It is advisable to consult with a doctor about temporarily discontinuing medication prior to surgery or radiological procedures with contrast agents. This medication may cause side effects such as diarrhea, nausea, headache, upper respiratory tract infections, so if symptoms are severe, consultation with healthcare professionals is necessary.

Serious side effects

Hives, angioedema, anaphylaxis, exfoliative skin disease (including Stevens-Johnson syndrome), acute pancreatitis, acute renal failure, difficulty breathing, unstable angina, acute renal failure, acute pancreatitis, difficulty breathing, jaundice, severe edema, increased blood pressure, severe allergic reactions, serious skin adverse reactions, acute pancreatitis, severe hypoglycemia, severe and disabling arthralgia, bullous pemphigoid

Mild side effects

• Diarrhea
• upper respiratory tract infections
• headaches
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. It is also advisable to store it at room temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the medication's efficacy for a longer period.

Appearance

An oval film-coated tablet of bright pink color, engraved with 575 on one side

Package unit

56 tablets (14 tablets/PTPx4)