Sandoz Amlodipine Tablets 5 mg (Amlodipine Besylate)

Adult dosage

Administer 5 mg orally once daily as amlodipine, and may increase to a maximum of 10 mg daily based on patient response. Adjust as appropriate according to age and symptoms.

This medication should not be used by certain patients. For example, individuals who have had allergic reactions to this drug or similar classes of medications should avoid it. Women who are pregnant, potentially pregnant, or breastfeeding should not take this drug. Patients with very poor liver function, severe aortic stenosis, and those in shock should also avoid using this drug. Additionally, patients with severe hypotension, those requiring dialysis due to renal failure, and elderly patients should exercise extra caution when taking this medication. This drug generally has good tolerability, but some patients may experience side effects such as flushing, fatigue, edema, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea. Rarely, adverse reactions such as excessively low blood pressure, vasculitis, neurological disorders, erectile dysfunction, gastrointestinal issues, and skin rashes have been reported. It is important to consult healthcare professionals immediately if any abnormal symptoms occur while taking this medication. Patients with heart failure or impaired liver function should be especially cautious when administering this drug, and its effects may appear gradually, thus it is not suitable for emergency situations like acute angina. This drug may interact with other medications, so if you are taking other drugs, make sure to inform your healthcare provider. Particularly, taking it with grapefruit juice can increase blood pressure-lowering effects, so it is advisable to avoid this combination. Women who are pregnant or breastfeeding should be aware that the safety of this drug is not firmly established, and it is recommended to substitute with other safe medications or discontinue breastfeeding if possible. Safety in children has not yet been established, and for the elderly, routine dosing is generally appropriate. In cases of overdose, severe hypotension and cardiac problems may occur, necessitating immediate emergency treatment, and blood dialysis will not eliminate this drug, requiring specialized care. Lastly, this medication is not known to pose carcinogenic or mutagenic risks, and is considered safe when taken in appropriate doses in healthy adults.

Serious side effects

• Urticaria
• angioedema
• erythema multiforme
• toxic epidermal necrolysis
• dyspnea
• difficulty breathing
• jaundice
• hepatitis
• sudden and severe headaches
• seizures

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to prevent exposure to air or humidity. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

White octagonal tablet with a score line on one side

Package unit

30 tablets/bottle, 100 tablets/bottle