Actogreen Tablet (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once daily, regardless of meals. As monotherapy, it may start at a dose of 15 mg once daily, and if the effect is insufficient, the dose may be increased to 30 mg once daily. In combination therapy with sulfonylureas, metformin, or insulin, a dose of 15 mg is administered once daily, and the maximum recommended dosage should not exceed 30 mg once daily.

Child dose

Not recommended for use in children under 18 years due to lack of experience.

This drug is used for the treatment of type 2 diabetes and is effective only when insulin is present to lower blood sugar. When taking this medication, heart failure may occur or worsen, so if symptoms such as sudden weight gain, shortness of breath, or leg swelling appear, consult a physician immediately. Patients with heart failure or a history of heart failure should not take this medication. Additionally, this drug can cause fluid retention, which may worsen heart failure; thus, caution is needed for patients with cardiovascular diseases. Patients with bladder cancer or a history of bladder cancer should also not use this medication. Patients with poor liver function or severely impaired kidney function should avoid this medication, and if signs of liver dysfunction appear, they should undergo testing immediately. This medication carries a risk of hypoglycemia; therefore, when used with other hypoglycemics like insulin or sulfonylureas, be vigilant for signs of hypoglycemia, and adjust the dosages of other medications if necessary. Edema or weight gain may occur, so it is essential to inform healthcare providers of these symptoms. Premenopausal women should use appropriate contraception, as this medication may promote ovulation, increasing the risk of pregnancy. Women who are pregnant or may become pregnant should not take this medication, and breastfeeding mothers should consult a physician. The safety and efficacy of this medication in children under 18 years of age have not been established. When administering to elderly patients, careful monitoring is necessary, especially for patients over 75 years of age. In case of overdose, appropriate treatment should be provided based on symptoms. This medication may interact with other drugs, so if taking other medications, patients must inform their physician or pharmacist.

Serious side effects

• Congestive heart failure
• heart failure
• difficulty breathing
• edema
• severe edema
• urinary abnormalities
• hives
• severe allergic reactions
• extreme swelling
• chest tightness

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This drug should be stored in a container that shields it from light and air, avoiding areas with high humidity. The storage temperature should ideally be around 25 degrees Celsius, but storing between 15 and 30 degrees Celsius is recommended.

Appearance

White round tablet

Package unit

(Domestic) 30 tablets/bottle, 300 tablets/bottle (Export) 30 tablets (10 tablets x 3 PTP)