Glitarzone Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once daily, regardless of meals. It is started at a dose of 15 mg once daily as monotherapy, and if the effect is insufficient, the dose may be increased to 30 mg once daily. For combination therapy, it is administered at a dose of 15 mg once daily with sulfonylureas, metformin, and insulin. The maximum recommended dose should not exceed 30 mg once daily.

Child dose

There is no experience in children under 18 years; therefore, its use is not recommended.

This medication is used to treat type 2 diabetes and only shows effectiveness in lowering blood sugar with the assistance of insulin. This medication may put some patients at risk of worsening or newly developing congestive heart failure, so it should not be used in patients with heart failure or a history of heart failure. After starting treatment or increasing the dose, it is crucial to closely monitor for sudden weight gain or symptoms of heart failure, such as shortness of breath, and consult a doctor immediately if symptoms arise. Additionally, this medication can cause fluid retention, leading to edema, so patients with edema or a high risk of heart disease should use it cautiously. Patients with active bladder cancer or a history of bladder cancer should not use this medication, and they should inform their doctor immediately if they experience hematuria or urinary disorders during treatment. Patients with impaired liver function should also exercise caution and have regular liver function tests before and during treatment. The risk of hypoglycemia may increase when this medication is used in combination with other diabetes medications, so dosage adjustments of the concomitant medications may be necessary. Premenopausal women should be aware that this medication may induce ovulation and increase the possibility of pregnancy; thus, appropriate contraceptive measures are recommended. Elderly patients or those with reduced kidney function should also be cautious, and regular monitoring of weight gain, edema, and symptoms of heart failure should be conducted during the use of this medication. In cases of overdose, no specific symptoms may be observed; however, if unusual symptoms occur, immediate medical attention is required. This medication is taken once daily, and in case a dose is missed, care should be taken not to double the next day's dose. Finally, keep it out of reach of children and store it in its original container to maintain quality.

Serious side effects

Congestive heart failure, signs and symptoms of heart failure (including excessive and rapid weight changes, shortness of breath, edema), severe edema, severe allergic reactions (such as hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe dermatologic reactions (including severe rashes with fever, blisters, skin peeling, oral/ocular mucosal pain), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, cough with fever).

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that prevents light and air from entering, and it should be kept away from humid areas. The storage temperature should be between 15 to 30 degrees, with a preference for around 25 degrees.

Appearance

White round tablet

Package unit

30 tablets/bottle