Question 1

What are the indications and effects of Culprofen Tablet (Dexibuprofen)?

Accepted Answer

This medication is used for chronic inflammatory diseases such as chronic multi-joint arthritis, rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It also helps relieve painful swelling and inflammation following trauma or surgery. Additionally, it plays a supportive role in the treatment of infections accompanied by inflammation, pain, and fever. It is effectively used for various inflammatory diseases and pain relief.

Question 2

What are the dosage and administration instructions for Culprofen Tablet (Dexibuprofen)?

Accepted Answer

Adults: Administer 400 mg per dose orally 2～3 times daily as dexibuprofen. Do not exceed 1,200 mg of dexibuprofen per day.

Question 3

What are the side effects of Culprofen Tablet (Dexibuprofen)?

Accepted Answer

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcers, perforations, dizziness, fatigue, headaches, shock, aplastic anemia, hemolytic anemia, granulocytopenia, leukopenia, agranulocytosis, pancytopenia, thrombocytopenia, impaired platelet function, eosinophilia, dyspepsia, abdominal distension, heartburn, epigastric pain, diarrhea, constipation, loss of appetite, nausea, vomiting, abdominal pain, gastric discomfort, esophagitis, esophageal stricture, exacerbation of diverticulitis, nonspecific hemorrhagic colitis, ulcerative colitis, Crohn's disease, peptic ulcer, gastrointestinal bleeding, perforation, bloody stools, gastritis, pancreatitis, thirst, stomatitis, erythema multiforme, systemic lupus erythematosus, hair loss, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, eosinophilia, drug rash with systemic symptoms, rash, urticaria, itching, purpura, asthma attacks, eczema, anaphylactic reactions, photosensitivity reactions, jaundice, elevated ALT, elevated AST, elevated ALP, liver dysfunction, hepatitis, rhinitis, bronchospasm, acute pneumonia, neglect, cancer invasion, hearing loss, tinnitus, taste disturbances, fatigue, drowsiness, headaches, dizziness, anxiety, agitation, confusion, depression, aseptic meningitis, psychiatric disturbances, restlessness, excitement, sense of direction impairment, reversible toxic myopathy, low blood pressure, high blood pressure, palpitations, acute renal failure, oliguria, hematuria, proteinuria, elevated BUN, elevated serum creatinine, hyperkalemia, decreased urine output, generalized edema, shortness of breath, lethargy, renal papillary necrosis, nephrotic syndrome, interstitial nephritis, peripheral edema, acute pulmonary edema, fluid retention, decreased reproductive capacity in women, periorbital edema, fatigue, fever, nosebleeds, exacerbation of inflammation, crying, facial swelling, dyspepsia, itching, anaphylactic shock, rash, diarrhea, vomiting

Question 4

What precautions should be taken when using Culprofen Tablet (Dexibuprofen)?

Accepted Answer

This medication carries a risk of gastrointestinal bleeding in individuals who regularly consume more than 3 alcoholic beverages per day; therefore, consultation with a doctor or pharmacist is essential.

This medication may affect the cardiovascular system and increase the risk of myocardial infarction or stroke, so particular caution is needed for individuals with cardiovascular diseases or risk factors.

This medication can cause severe gastrointestinal problems like gastrointestinal bleeding, ulcers, or perforation, thus older adults or individuals with a history of gastrointestinal conditions should take it with extra caution.

Individuals with gastrointestinal ulcers or bleeding, severe blood disorders, liver disease, kidney disease, heart failure, or high blood pressure should not take this medication.

Combining this medication with aspirin or other non-steroidal anti-inflammatory drugs can increase the risk of serious side effects, so it is advisable not to take them together.

During the course of this medication, breastfeeding should be discontinued or discussed with a doctor, and caution is required while driving or operating machinery as dizziness or fatigue may occur.

Individuals with a history of blood disorders, liver disease, kidney disease, hypertension, heart failure, as well as elderly patients, children, pregnant women, and alcoholics should consult an expert before taking this medication.

If symptoms of shock, severe skin rash, gastrointestinal bleeding, liver dysfunction, kidney dysfunction, or neurological disturbances appear during the course of this medication, it should be discontinued immediately and a doctor consulted.

This medication should be taken for the shortest duration and at the lowest effective dose; long-term use requires regular blood tests and monitoring of liver and kidney functions.

After the 20th week of pregnancy, it may affect the fetal kidney function, so the duration and dosage should be minimized, and the amniotic fluid condition should be monitored if necessary.

In case of overdose, even without symptoms, it is crucial to visit a medical institution quickly for appropriate treatment.

This medication should be stored in a cool, dry place out of reach of children and in a sealed container to prevent exposure to air and moisture; avoid transferring to another container.

Culprofen Tablet (Dexibuprofen)

Summary

Ingredients

Efficacy & effects

How to take

Adult dose

Precautions

Side effects

Storage

Appearance and packaging

Appearance

Package unit

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