Isophen Tablet (Dexibuprofen)

Adult dose

Administer 400 mg of dexibuprofen orally 2 to 3 times a day. However, do not exceed 1,200 mg of dexibuprofen in one day.

Caution is advised for those who consume more than three alcoholic beverages daily, as this may lead to gastrointestinal bleeding; consultation with a physician or pharmacist is essential. Non-steroidal anti-inflammatory drugs, including this medication, may increase the risk of serious cardiovascular events, particularly in those at risk for heart disease or stroke. If cardiovascular symptoms occur while taking this medication, one must seek medical attention immediately, and this caution applies even to individuals without a history of cardiovascular disease. Patients with hypertension, heart failure, ischemic heart disease, etc., should use this medication with caution and avoid high-dose usage. This medication may cause serious gastrointestinal side effects such as bleeding, ulcers, or perforation, especially in the elderly or those with a history of gastrointestinal disease. Long-term use may increase the risk of gastrointestinal adverse reactions, so patients should be vigilant for any gastrointestinal symptoms while on this medication. Individuals with a history of gastrointestinal ulcers or bleeding, or those with severe liver, kidney, or heart disease, should not take this medication. Those with hypersensitivity to this drug or history of asthma, or allergies to aspirin or other non-steroidal anti-inflammatory drugs, should not take it. Pregnant women who are in their sixth month or later should not take this drug, as it may harm the fetus. Caution must be exercised when taking this medication in combination with aspirin or other non-steroidal anti-inflammatory drugs, as this may increase the risk of gastrointestinal bleeding and reduce the drug's effectiveness. It is prohibited to take this medication with high-dose methotrexate due to the risk of fatal toxicity. During usage, nursing should be stopped, or the drug discontinued, and caution is necessary when driving or operating machinery as dizziness or fatigue may occur. Long-term high-dose use may lead to headaches, so caution is necessary. Individuals with blood disorders, liver or kidney disease, hypertension, heart failure, the elderly, and pregnant women or those planning pregnancy should consult a physician, dentist, or pharmacist before taking this drug. If symptoms such as shock, severe allergic reaction, gastrointestinal bleeding, skin rash, liver dysfunction, kidney problems, or cardiovascular symptoms occur while taking this medication, it must be discontinued immediately, and medical consultation is required. It is advisable to take this medication at the minimum effective dose for the shortest period possible, and routine blood tests along with liver and kidney function tests are necessary during chronic disease treatment. Blood pressure should be regularly monitored as this medication may worsen hypertension, and caution is needed if fluid retention or swelling occurs. After 20 weeks of pregnancy, this medication may affect the fetal renal function, so amniotic fluid levels need to be monitored during use, and should any symptoms appear, it should be discontinued immediately. In case of overdose, medical treatment should be sought promptly even if symptoms are absent, and it should be stored in a cool, dry place out of the reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/mucosal areas, difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Dyspepsia
• abdominal bloating
• heartburn
• epigastric pain
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is also important to keep it at room temperature, specifically between 1 to 30 degrees Celsius, to maintain its efficacy.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle