Atostin Tablet 20 mg (Atorvastatin Calcium Hydrate)

Adult dose

For hyperlipidemia, the recommended initial dose is 10 mg once daily; for patients needing greater LDL cholesterol reduction, it can be started at 20 mg or 40 mg once daily (only for cases requiring more than 45% LDL cholesterol reduction). The administered dosage should be adjusted within the range of 10 to 80 mg once daily. For patients with homozygous familial hypercholesterolemia, the dose is 10 to 80 mg once daily. Based on treatment goals and response, lipid levels should be assessed at intervals of 2 to 4 weeks to adjust the dosage accordingly. The goal of treatment is to reduce LDL cholesterol levels; thus, monitoring LDL cholesterol levels during treatment initiation and response evaluation is recommended. However, if LDL cholesterol levels cannot be obtained, total cholesterol levels can be used to monitor treatment response. For patients with homozygous familial hypercholesterolemia, the dosage of this medication is 10 to 80 mg once daily, administered in conjunction with other lipid-lowering treatments (e.g., LDL apheresis) or when such lipid-lowering treatments are not feasible.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17), the recommended initial dose is 10 mg once daily, with a maximum dose of 20 mg per day. Dosage should be adjusted based on treatment goals with intervals of 4 weeks or more.

This medication may have the potential for muscle problems; therefore, if symptoms of muscle pain or weakness occur, you should inform your doctor immediately. This medication may affect liver function, and it should not be administered to patients with liver disease or elevated liver function tests, and regular liver function tests should be conducted during treatment. Women who are pregnant or may become pregnant and those who are nursing should not use this medication, and women of childbearing potential should use appropriate contraception during treatment. This medication is not to be administered to children, especially those under the age of 10. Patients with a history of alcoholism or liver disease should use this medication with caution, and the elderly should also be cautious due to an increased risk of muscle problems. This medication may alter blood concentrations when taken with certain drugs; thus, if you are taking other medications, you must consult your doctor or pharmacist. No specific antidote is available in the case of overdose, and treatment should be provided based on symptoms, with monitoring of liver function and muscle condition. This medication should be kept out of the reach of children and should be stored in its original container for safety. If symptoms such as muscle pain, fatigue, or fever appear while taking this medication, inform medical personnel immediately, and if necessary, blood tests should be conducted to check for muscle damage. This medication may increase blood sugar levels in some patients; therefore, patients at risk for diabetes should manage their blood sugar levels thoroughly. This medication may cause rare respiratory side effects such as interstitial lung disease; thus, if breathing difficulties or persistent coughing occur, consult your doctor immediately. If blistering rashes or severe allergic reactions occur while taking this medication, you should stop taking it and inform medical personnel immediately. This medication can cause serious muscle damage such as myopathy or rhabdomyolysis; therefore, if severe muscle pain occurs or if muscle-related levels are significantly elevated in blood tests, the medication should be discontinued.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral or ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning headaches, seizures, loss of consciousness, vision disturbances, paralysis, urination.

Mild side effects

• Weakness
• fatigue
• chest pain
• tiredness
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain
• loss of appetite

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps to preserve the medication's effectiveness for a long time.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle