Kasept Tablets 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before sleep. For 4 to 6 weeks, administer the dose of 5 mg and evaluate clinical responses during this period. Afterward, it may be increased to 10 mg. If increasing to 10 mg daily, monitor for gastrointestinal adverse reactions. Women over 85 years who are underweight should not exceed 5 mg daily and require careful monitoring.

Child dose

There is no experience using this medication in pediatric patients.

This medication contains Donepezil Hydrochloride Monohydrate as the active ingredient and is used to treat symptoms of Alzheimer's type dementia. This medication should not be used in certain patients. For example, patients who are allergic to this medication or its ingredients, pregnant or breastfeeding women, and patients with lactose intolerance should not be administered this medication. Patients with heart disease or those with bradycardia syndrome and heart conduction disorders should use this medication with caution because it can slow down heartbeats or cause arrhythmias. Patients taking non-steroidal anti-inflammatory drugs (NSAIDs) or with a history of peptic ulcers should be cautious due to the risk of gastrointestinal bleeding or exacerbation of ulcers. Patients with a history of asthma or obstructive lung disease should use this medication cautiously as it may worsen symptoms due to bronchoconstriction or increased mucus secretion. Moreover, patients with extrapyramidal disorders such as Parkinson's disease may experience worsening of symptoms due to the cholinergic effects of this medication, so caution is advised. This medication contains the dye Yellow No. 5, and patients allergic to this ingredient should handle it carefully. During administration, various adverse reactions may occur. Commonly reported reactions include dizziness, nausea, vomiting, diarrhea, loss of appetite, insomnia, bradycardia, cardiac arrhythmia, liver dysfunction, and rash. In severe cases, serious side effects such as syncope, heart block, brain hemorrhage, cerebral seizures, acute pancreatitis, acute kidney failure, and rhabdomyolysis may occur, so if unusual symptoms appear, immediate consultation with healthcare professionals is required. This medication should be used under the supervision of an experienced physician for dementia treatment, and if there is no therapeutic effect or if side effects are significant, discontinuation should be considered. Patients with cardiovascular diseases may require particular heart monitoring, and patients with gastrointestinal or bladder-related issues should also use it cautiously. This medication may affect the ability to drive or operate machinery, so caution is necessary at the beginning of treatment or when dosage changes are made. It is advisable for pregnant or breastfeeding women to avoid this medication, and if necessary, a consultation with a specialist should be conducted. This medication can affect liver and kidney function, so regular testing may be required. In case of overdose, symptoms like nausea, vomiting, sweating, bradycardia, respiratory depression, and seizures may appear, requiring immediate emergency treatment. Interactions with other medications may occur, so it is essential to inform healthcare professionals if any other medications are being taken. Lastly, this medication should be stored out of the reach of children, and it is safer not to transfer it to another container.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• hepatitis
• jaundice
• cerebral seizures
• brain hemorrhage
• myocardial infarction
• heart failure
• heart block

Mild side effects

• Nausea
• vomiting
• loss of appetite
• diarrhea
• headache
• fatigue
• insomnia
• drowsiness
• dizziness
• anxiety

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. This storage condition helps maintain the medication's effectiveness and prevent deterioration.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle