Miraset Tablets 5 mg (Donepezil Hydrochloride Hydrate)

Adult dose

Administer 5 mg once daily before bedtime as Donepezil Hydrochloride. Administer 5 mg for 4-6 weeks, and after assessing clinical response, the dose can be increased to 10 mg. When increasing the dose to 10 mg per day, caution should be taken regarding gastrointestinal adverse reactions. Women over the age of 85 who are underweight should not exceed 5 mg per day and require careful monitoring.

Child dose

There is no experience of use in pediatric patients.

This medication is used for the treatment of symptoms of Alzheimer's type dementia, with Donepezil Hydrochloride as its active ingredient. This medication should not be used by certain patients. For example, individuals who are allergic to this medication or its components, women who are pregnant or breastfeeding, and those with lactose intolerance or genetic metabolic disorders should not take it. Patients with heart disease or certain conditions such as asthma, peptic ulcer, or Parkinson's disease should use this medication with caution, and care should be taken in case of allergic reactions. Since this medication can affect the heart, there is a possibility of causing heart problems such as bradycardia or arrhythmias, so it is important for patients with heart disease to undergo an ECG examination under a doctor's instructions. It may affect the gastrointestinal system, leading to nausea, vomiting, diarrhea, or gastrointestinal bleeding, thus patients with a history of peptic ulcers should take caution. This medication can affect the central nervous system, potentially causing neurological symptoms such as hallucinations, insomnia, anxiety, depression, dizziness, and seizures, so immediate consultation with healthcare professionals is required when symptoms occur. Additionally, serious adverse reactions have been reported such as muscle pain, muscle rigidity, respiratory distress, acute pancreatitis, and acute renal failure, so consultation should be sought immediately if abnormal symptoms occur. This medication may interact with other drugs, particularly those related to the heart, antibiotics, antidepressants, and anticholinergic medications, and should be carefully managed by informing healthcare professionals when taking these medications. It is preferable for pregnant or breastfeeding women not to use this medication, and if absolutely necessary, thorough consultation with a specialist is required. Safety in pediatric use has not been established, so it should not be administered to children. This medication may affect driving or machinery operation capabilities, so caution is needed when starting or changing dosages. In case of overdose, severe symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, so it is important to adhere to the prescribed dosage and contact a medical institution immediately in case of overdose. This medication should be stored out of reach of children, and it is safer not to transfer it to another container.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, gastrointestinal bleeding, peptic ulcers, perforation of the duodenum, hepatitis, liver dysfunction, jaundice, cerebral seizures, cerebral hemorrhage, cerebrovascular disorders, severe symptoms of extrapyramidal disorders, neuroleptic malignant syndrome, rhabdomyolysis, respiratory distress, acute pancreatitis, acute renal failure, sudden death, cardiac arrest, Torsades de pointes, atrial fibrillation

Mild side effects

• Loss of appetite
• nausea
• vomiting
• diarrhea
• dizziness
• insomnia
• drowsiness
• headache
• fatigue
• muscle pain

This medication should be stored in a tightly sealed container to prevent air from entering, and it is advisable to keep it at room temperature between 1°C and 30°C. Proper storage helps maintain the medication's effectiveness.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle