Septpezil Tablet 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil hydrochloride, administer 5 mg once daily before bedtime. If unusual dreams, nightmares, or sleep disturbances occur, consider morning administration. Donepezil concentration reaches a steady state after 15 days of administration, so administer 5 mg for 4-6 weeks. After evaluating clinical response during this period, the dosage may be increased to 10 mg. When increasing to 10 mg, pay attention to gastrointestinal adverse reactions.

This medication contains Donepezil hydrochloride as the active ingredient, which is used to alleviate symptoms of Alzheimer's dementia. This medication should not be administered to certain patients. For example, it should not be used in persons who have allergies to this drug or its ingredients, pregnant women or women who may become pregnant, and patients with lactose intolerance. Patients with heart disease or heart conduction disorders should use this medication with caution. This medication may slow down heart rate or induce arrhythmia. Patients taking non-steroidal anti-inflammatory drugs or with a history of gastric ulcers should be cautious due to the risk of gastrointestinal bleeding or worsening ulcers. Patients with asthma or a history of obstructive pulmonary disease should be administered this medication carefully as they may experience exacerbated symptoms due to bronchoconstriction and increased mucus secretion. Patients with extrapyramidal disorders such as Parkinson's disease may need to use this medication cautiously as it may worsen symptoms. Serious adverse reactions, such as fainting, heart abnormalities, gastrointestinal bleeding, liver dysfunction, cerebrovascular problems, movement disorders, respiratory distress, acute pancreatitis, and acute renal failure, may occur while taking this medication, so one should consult a doctor immediately if any symptoms arise. Additionally, various side effects, such as nausea, vomiting, diarrhea, dizziness, insomnia, hallucinations, aggressive behavior, myalgia, etc., have been reported, so careful observation is required. This medication may affect the cardiovascular system, causing side effects such as bradycardia or heart block; therefore, patients with heart disease may need regular ECG tests. Driving or operating machinery may be affected, so caution is necessary during initial use or when changing dosages. Pregnant or nursing women are advised not to use this medication, and if it is essential, it should only be decided after consultation with a specialist. This medication may interact with various drugs, so if taking other medications, one must inform healthcare professionals. In case of overdose, symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur; therefore, one should visit a medical facility immediately for appropriate treatment. This medication has not been established as safe for children, so it should not be used.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reactions), high fever with severe rash, blisters, pain in mouth/eye mucosa (severe skin adverse reactions), difficulty breathing or shortness of breath, asthma attack, cough with fever accompanied respiratory distress (respiratory issues), yellowing of the skin or eyes (jaundice), extreme lethargy (liver issues (jaundice)), sudden and

Mild side effects

• Headache
• dizziness
• insomnia
• drowsiness
• loss of appetite
• nausea
• vomiting
• diarrhea
• abdominal pain
• fatigue

This medication should be stored in a sealed container to prevent air and moisture ingress. It is also advisable to store it at room temperature between 1°C and 30°C. This storage will help maintain the medication's effectiveness.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle