Alfurox XL Tablet 10mg (Alfuzosin Hydrochloride)

Adult dose

The recommended dose is 10mg once daily, taken immediately after the evening meal. Do not chew; swallow the tablet whole. When administered as adjunctive therapy to catheterization for acute urinary retention associated with benign prostatic hyperplasia, the recommended dose is 10mg once daily, taken after a meal starting on the first day of catheterization. Take for 2-3 days while the catheter is in place and for 1 day after catheter removal, for a total of 3-4 days.

This medication contains an alpha-1 blocker and should not be used in certain patients. For example, it is contraindicated in patients who are allergic to this drug or its components, patients with orthostatic hypotension, those with severely impaired liver or kidney function, patients with intestinal obstruction, those taking other alpha blockers, and patients who are on strong CYP3A4 inhibitors. Additionally, certain patients, particularly those receiving treatment for hypertension, may experience symptoms of orthostatic hypotension within hours of taking this medication for the first time. Symptoms such as dizziness, fatigue, and sweating may occur, making it important to rest in a lying position until these symptoms completely resolve. Older patients may experience these symptoms more frequently, so greater caution is warranted. Patients with symptoms of orthostatic hypotension or those taking antihypertensive agents or nitrates should use this medication carefully. It should not be prescribed alone to patients with coronary artery disease, and if angina symptoms worsen, the medication should be discontinued immediately. Care is also needed in patients with prolonged QT intervals or those taking QT interval-prolonging drugs. Common side effects of this medication include dizziness, headache, nausea, constipation, and fatigue, while rare adverse reactions such as hypotension, skin rash, and erectile dysfunction have also been reported. Continuous erection linked to erectile dysfunction may occur, and if this happens, the patient should inform their physician immediately. Patients planning cataract surgery should inform their ophthalmologist about their use of this medication beforehand, as a rare complication known as intraoperative floppy iris syndrome may occur, so that appropriate measures can be taken. This medication should be swallowed whole and should not be crushed, chewed, or made into powder, as rapid absorption may increase the risk of side effects. Patients who have experience with other alpha blockers should be cautious of hypotension risks. This medication should not be taken with specific antihypertensive drugs or strong CYP3A4 inhibitors, and caution is advised when used in conjunction with antihypertensive agents or nitrate preparations. It is not indicated for use in women who are pregnant or nursing, nor in children. During initial use, dizziness or weakness may occur, so care should be taken when driving or operating machinery. In case of overdose, the patient should be hospitalized immediately to maintain a lying position and receive treatment for hypotension, as this medication is not removed by dialysis. Lastly, this medication should be kept out of reach of children, and it is recommended not to transfer it to other containers for safety and quality maintenance.

• fainting
• dizziness
• headache
• vertigo
• syncope
• tachycardia
• angina
• intraoperative floppy iris syndrome
• upper respiratory tract infection
• bronchitis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to maintain storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

This medication is a film-coated tablet formed of three layers, consisting of one white layer sandwiched between two yellow layers, and has a biconvex circular shape.

Package unit

30 tablets per bottle, 100 tablets per bottle