Piogreen Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is taken as an oral dose once daily regardless of meals. It may be initiated with an oral dose of 15 mg once daily for monotherapy, and if not sufficiently effective, it may be increased to 30 mg once daily. When used in combination with sulfonylureas, metformin, or insulin, the dosage is also 15 mg once daily, with a maximum recommended dose of 30 mg once daily.

Child dose

Use in pediatric patients under 18 years of age is not recommended due to lack of experience.

This drug may put stress on the heart for some patients, potentially causing or worsening congestive heart failure. Therefore, if severe weight gain, shortness of breath, or swelling occurs during treatment, medical attention should be sought immediately. Patients with heart failure or symptoms of heart failure should not use this medication and must be monitored closely for heart failure symptoms while taking this drug. Additionally, this drug can cause fluid retention as a side effect, which may lead to edema, so consultation with a physician is necessary if swelling symptoms appear. When used in combination with insulin or other blood glucose lowering agents for diabetes treatment, the risk of hypoglycemia may increase, therefore patients should be well aware of hypoglycemia symptoms and management methods. This drug may affect liver function, so regular liver function tests should be conducted before and during treatment, and any signs of liver dysfunction should be reported to a physician immediately. Patients with a history of bladder cancer or current bladder cancer should not use this medication, and if symptoms like blood in urine or urination difficulties appear, medical attention should be sought immediately. Premenopausal women should be aware that this drug may induce ovulation, creating a possibility of pregnancy; therefore, appropriate contraceptive methods should be used. Elderly patients, as well as those with impaired kidney or liver function, should use this drug cautiously, with regular health status checks required. During treatment, patients should be closely monitored for weight gain, edema, and heart failure symptoms, and if any abnormalities occur, they should consult healthcare professionals immediately. This drug is taken once daily, and care must be taken not to double the dose if a dose is missed the following day. Regular meals and continuous blood sugar monitoring are required while taking this medication, and in stressful situations like infections or surgeries, consultation with healthcare professionals is necessary.

Serious side effects

Congestive heart failure, worsening of heart failure, edema, severe swelling, chest tightness, difficulty breathing, fluid retention, symptoms and signs of heart failure (excessive and rapid weight changes, shortness of breath, edema), severe allergic reactions, hives, pallor, cold sweat, severe skin reactions (fever, severe rash, blistering, skin peeling, mucosal pain in mouth/eyes), liver abnormalities (jaundice, yellowing of skin or eyes, extreme drowsiness),

Mild side effects

• Upper respiratory tract infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• urinary tract infection
• hypoglycemia
• back pain

This medication is sensitive to light, so it should be stored in a container that does not allow light to pass through. Additionally, it should be safely kept at room temperature between 1 to 30 degrees Celsius.

Appearance

White to dark white round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle