Pioglitazone (Pioglitazone Hydrochloride) Tablets

Adult dose

This medication is taken orally once daily regardless of meals. It can start at 15 mg once daily for monotherapy, and if effectiveness is insufficient, it can be increased to 30 mg once daily. The initial dosage for combination therapy is also 15 mg once daily and can be used with sulfonylureas, metformin, or insulin. The maximum recommended dosage does not exceed 30 mg once daily.

Child dose

There is no experience using this medication in children under 18 years, so it is not recommended for use.

This medication is used for the treatment of Type 2 diabetes and helps the action of insulin. However, it can affect heart function in some patients, potentially causing or worsening congestive heart failure, so it should not be used in patients with heart failure or a history of heart failure. While taking this medication, patients should be closely monitored for symptoms of heart failure such as sudden weight gain, shortness of breath, or swelling, and should consult a doctor immediately if these symptoms occur. Additionally, this medication can cause fluid retention and swelling, so caution is advised in patients with existing edema. Active bladder cancer patients or those with a history of bladder cancer should not be administered this medication, and any signs of hematuria or urinary problems during treatment should be reported immediately to a doctor. Patients with poor liver function or severe kidney impairment should also avoid this medication, as well as those with diabetic ketoacidosis or Type 1 diabetes. Women who are pregnant or may become pregnant should not take this medication, and premenopausal women should use appropriate contraception as this medication may stimulate ovulation, increasing the risk of pregnancy. Regular monitoring of blood sugar and liver function tests is required during treatment, and it may be necessary to adjust dosages to reduce the risk of hypoglycemia when combined with insulin or other hypoglycemic agents. This medication may also cause side effects such as weight gain, headache, upper respiratory infections, edema, and others, so consultation with a doctor is necessary if these symptoms occur. Elderly patients or those with decreased kidney function should use it carefully, and immediate medical assistance should be sought in case of overdose. Finally, this medication has not been established as safe and effective for children under 18 years of age, thus it is not recommended for this age group.

Serious side effects

Congestive heart failure, worsening of heart failure, severe edema, cardiovascular abnormalities, symptoms and signs of heart failure (including excessive and rapid weight change, shortness of breath, and swelling), severe allergic reactions (hives), liver abnormalities (jaundice, liver failure, worsening of liver disease), severe skin reactions (severe rash, blisters, peeling skin), serious neurological symptoms (stroke), respiratory issues (difficulty breathing, respiratory distress, asthma attacks, coughing with fever).

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• lower back pain

This medication should be stored in a container that blocks light and air, avoiding humid places. The optimal storage temperature is between 15 and 30 degrees Celsius, with a preference for around 25 degrees.

Appearance

White round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle