Hyaron First Injection (Sodium Hyaluronate) (Pre-filled)

Adult administration

Usually, for adults, 1 vial is administered once a week for 3 consecutive weeks into the knee joint or shoulder joint, but the number of administrations should be adjusted appropriately according to symptoms.

This medication should not be used in patients who have experienced allergic reactions to its components. It should be used with caution in patients with a history of allergic reactions to other medications, liver dysfunction or a past history of liver disease, and in patients with skin diseases or infections at the injection site. Serious shock symptoms may arise when using this medication, so patients should be monitored closely, and if any unusual symptoms appear, use should be stopped immediately, and appropriate treatment should be obtained. Allergic symptoms such as swelling of the face or around the eyes, rashes, and itching may occur, so if these symptoms appear, drug use should be stopped and medical assistance should be sought. There may be temporary pain, swelling, redness, heat, and a sensation of pressure at the injection site, and symptoms such as nausea, vomiting, and fever may also occur. If this medication is administered to a joint with severe inflammation, the inflammation may worsen, thus it is better to use it after the inflammation has subsided. After the injection, measures such as stabilizing the injection site should be taken to reduce pain. If the medication leaks outside the joint cavity, it may cause pain, so it must be injected accurately into the joint. Injections should only be performed in sterile conditions on the knee joint or shoulder joint, and if symptoms do not improve, treatment should be discontinued after 3 administrations. If there is fluid accumulation in the joint, it is necessary to drain the fluid before injection. This medication should not be administered intravenously or used for eye treatments. A needle gauge of 22-23 is appropriate for injections. This medication may form sediment if mixed with certain disinfectants, so caution is necessary. Women who are pregnant or may become pregnant should only use this medication cautiously if the benefits are deemed greater than the risks, and breastfeeding should be avoided during medication use. Safety in children has not been established, so it should only be used cautiously when absolutely necessary. Elderly patients may have decreased bodily function, so special care should be taken when administering.

Serious side effects

• Urticaria
• swelling (severe swelling)
• shock (unknown frequency)

Mild side effects

Swelling (facial, eyelid, etc.), facial flushing, rash, itching, pain (mainly transient pain after administration), edema, redness, warmth, localized severe pressure sensation, nausea, vomiting, fever.

This medication should be stored in a sealed container to protect it from air and light exposure, and kept in a dark place away from direct sunlight. Additionally, it should be stored at room temperature between 1 degree and 30 degrees Celsius for safe use.

Appearance

A colorless, transparent liquid with viscosity inside a colorless, transparent glass vial sealed with rubber caps at both ends (part of the pre-filled syringe system).

Package unit

2ml/vial × 3 vials (for export), 9 vials