Daiserine Capsule (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein per day orally in 1∼2 divided doses after meals. Adjust the dose appropriately according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used by patients with certain diseases. For example, individuals with inflammatory bowel disease or bowel obstruction syndrome should not take this medication. Additionally, those experiencing unexplained abdominal pain or who are allergic to this medication, its ingredients, or Rhein-related medications should avoid it. Patients with liver disease or a history of liver problems should also refrain from using this medication. It is not recommended for children under 15 years old, and patients with lactose intolerance or certain genetic metabolic disorders should also avoid taking it. In cases of a history of small intestine or colon disorders, this medication should be used cautiously, and pregnant or breastfeeding women should also refrain from its use. Elderly individuals aged 65 years and above should reduce the dosage. This medication can affect the gastrointestinal system, potentially causing diarrhea, abdominal pain, serious gastrointestinal issues like gastrointestinal bleeding or ulcers. It is especially important to follow medical instructions when using this medication for a prolonged period. If diarrhea occurs, dehydration or electrolyte imbalance may develop, so if these symptoms appear, stop the medication immediately and consult a healthcare provider. Symptoms such as itching, rashes, and eczema may occur, and there may be an increase in liver enzyme levels, indicating potential liver function impacts. When taking this medication for an extended time, careful monitoring of liver health is necessary, and it is advisable to avoid alcohol consumption. If symptoms of liver damage occur, discontinue use immediately. Taking antacids or salts containing calcium, magnesium, or aluminum can hinder the absorption of this medication, so they should be taken at least 2 hours apart. Caution is needed when taking diuretics together, as the diuretic effect can be enhanced, leading to dehydration or hypokalemia. Additionally, combining with cardiac glycoside medications may increase the risk of arrhythmias, so care should be taken. Pregnant or breastfeeding women are advised against taking this medication, as it may affect the fetus or newborn. In cases of overdose, severe diarrhea may occur, requiring appropriate treatment, such as electrolyte replenishment.

Diarrhea, loose stool, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rashes, eczema, elevated serum liver enzymes

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. The recommended storage temperature is between 1 to 30 degrees Celsius to maintain the medication's effectiveness and safety for a longer time.

Appearance

A hard capsule with a yellowish brown content in the upper yellow and the lower light yellow.

Package unit

30 capsules/bottle, 300 capsules/bottle