Actozone 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medicine is taken orally once a day, regardless of meals. As monotherapy, it can be started at 15 mg once daily, and if the effect is insufficient, it can be increased to 30 mg once daily. In combination therapy, it is administered at 15 mg once daily with sulfonylureas, metformin, or insulin. The maximum recommended dose does not exceed 30 mg once daily.

Child dose

There is no experience in using this medicine in children under 18 years, so administration is not recommended.

This medicine is used for the treatment of type 2 diabetes and is effective in patients whose insulin is normally secreted. During the use of this medicine, heart failure may occur or worsen; therefore, patients with heart disease should consult with their doctor before administration. In particular, patients with existing symptoms of heart failure or a history of heart failure should not use this medicine. This medicine can cause fluid retention, leading to edema; thus, if symptoms of edema occur, medical personnel should be informed immediately. Furthermore, patients with a history of bladder cancer or currently having bladder cancer should not take this medicine. Patients with poor liver function or severely impaired kidney function should also avoid this medicine. Women who are pregnant or of childbearing potential should not take this medicine, and premenopausal women should use appropriate contraceptive methods as the risk of pregnancy may increase during use. This medicine may increase the risk of hypoglycemia when combined with other diabetes medications, so caution is needed when used together. Regular monitoring of blood sugar and liver function tests is required during treatment, and any symptoms such as weight gain, sudden edema, or shortness of breath should be reported to a doctor immediately. It is not recommended for use in children or adolescents under 18 years of age as safety and efficacy have not been established. Elderly patients, especially those over 75 years old, should use this medicine cautiously, and dosage adjustments may be necessary. In the case of overdose, immediate hospital visit for appropriate treatment is required. Finally, this medicine should be kept out of the reach of children and stored in its original container.

Serious side effects

Edema, congestive heart failure, symptoms and signs of heart failure, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe skin reactions (severe rash, blisters, skin peeling, pain in mouth/eye mucosa with fever), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever), liver abnormalities (yellowing of skin or eyes, generalized fatigue),

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• low back pain

This medicine should be stored in a container that protects it from light and air and should avoid humid areas. The storage temperature is generally between 15 to 30 degrees Celsius, with a recommended temperature of 25 degrees. Proper storage maintains the medicine's efficacy and safety.

Appearance

This medicine is a white, round tablet.

Package unit

30 tablets/bottle