Actigly 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once daily, regardless of meals. Starting from a dose of 15 mg once daily as monotherapy, it can be increased to 30 mg once daily if necessary. For combination therapy, the initial dose is 15 mg once daily. The maximum recommended dose should not exceed 30 mg once a day.

Child dose

There is no experience using this medication in children under 18 years of age; therefore, its use is not recommended.

This medication is used for the treatment of type 2 diabetes and is effective in lowering blood sugar only when insulin is present in the body. This medication can put stress on the heart, so it should not be used in patients with heart failure, and patients should seek medical attention immediately if symptoms of heart failure occur. Fluid retention can cause swelling, which may worsen heart failure, so symptoms such as swelling or shortness of breath should be monitored closely. Additionally, this medication should not be taken by patients with bladder cancer or those with a history of bladder cancer. As it can affect liver function, liver function tests should be done before treatment, and liver functions should be regularly monitored during treatment. Weight gain may occur while taking this medication, so changes in weight should be carefully observed. There is a risk of hypoglycemia, so when taken with insulin or other hypoglycemic agents, hypoglycemic symptoms should be monitored, and dose adjustments may be necessary if needed. Premenopausal women should use appropriate contraception as this medication may stimulate ovulation, leading to the possibility of pregnancy. Pregnant women or those who may become pregnant, patients with heart failure, liver impairment, severe kidney impairment, and patients with diabetic ketoacidosis should not use this medication. Patients should consult with a physician immediately if any abnormal symptoms or side effects appear while taking this medication, especially sudden weight gain, swelling, shortness of breath, or visible blood in the urine. Safety and efficacy have not been established in children and adolescents under 18 years of age. Elderly patients should be administered this medication with caution, and there may be drug interactions, so it is essential to consult with a doctor or pharmacist regarding any medications taken concurrently. This medication is taken once a day, and if a dose is missed, it should not be doubled the next day.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive weight change, difficulty breathing, and swelling), severe swelling, bladder cancer, severe symptoms and hospitalization due to hypoglycemia, fatal and non-fatal liver failure, liver damage symptoms (fatigue, loss of appetite, discomfort in the right upper abdomen, jaundice, dark urine), serious cardiac adverse reactions, severe allergic reactions (including hives), stroke, serious neurological symptoms, severe skin adverse reactions

Mild side effects

• Headache
• sinusitis
• myalgia
• pharyngitis
• upper respiratory infection
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• lower back pain

This medication should be stored in a container that does not allow light and air to enter, and care should be taken to avoid moisture. The optimal storage temperature is between 15 and 30 degrees Celsius, and it is advisable to keep it in a cool place around 25 degrees.

Appearance

This medication is a white, round tablet.

Package unit

30 tablets/bottle