Tobast Tablet 20mg (Atorvastatin Calcium Trihydrate)

Adult dose

For the treatment of hyperlipidemia, the recommended starting dose is 10 mg once daily; for patients needing a greater reduction in LDL cholesterol, starting doses can be 20 mg or 40 mg. The dosage range is 10 to 80 mg once daily, and adjustments should be individualized based on treatment goals and responses at intervals of 2 to 4 weeks. For patients with homozygous familial hypercholesterolemia, doses of 10 to 80 mg once daily are administered.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the recommended starting dose is 10 mg once daily, and the maximum dosage is 20 mg per day. Dosing adjustments should be made at an interval of 4 weeks or more.

This medication should be stopped immediately if any unusual symptoms in the muscles occur. Especially if accompanied by muscle pain, weakness, or severe fatigue, it is essential to consult a doctor. This medication should not be used in patients with certain diseases or those taking specific medications. For example, patients with severe liver disease, pregnant women, children under 10 years of age, and those taking certain antivirals should not use this drug. Patients with poor liver or kidney function should use this drug with caution and undergo regular tests to monitor liver function and muscle status. As this medication can affect liver function, regular liver function tests should be conducted before and during treatment, and the medication should be stopped immediately if symptoms of hepatitis appear. During treatment, alcohol consumption should be avoided, and additional caution is required if there is a history of liver disease. This drug can interact with certain antibiotics, antifungals, and antivirals, leading to increased drug levels and side effects risk; therefore, consultation with a physician is necessary when used in combination. It is advisable to avoid grapefruit juice as it may increase the blood concentration of this medication. Women of childbearing age who require contraception should use appropriate birth control methods while taking this medication, and it should be avoided if they are pregnant or planning to become pregnant. This medication is not recommended for breastfeeding women; if breastfeeding, it should be avoided. Elderly patients or those with reduced kidney function should be more cautious due to an increased risk of muscle-related side effects. In case of overdose, there is no specific antidote, and appropriate treatment should be administered based on symptoms, while monitoring liver function and muscle enzyme levels. This medication should be kept out of the reach of children and stored in its original container to prevent misuse or degradation in quality.

Serious side effects

• Hives
• angioedema
• anaphylaxis
• erythema multiforme
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• mucocutaneous syndrome
• severe edema
• jaundice
• severe skin adverse reactions

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication must be stored in a tightly sealed container to prevent air and moisture ingress. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle