Actipio Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once daily at a dose of 15 mg regardless of meals. If the initial dosage does not provide sufficient effect, it can be increased to 30 mg once daily. When used in combination with sulfonylureas, metformin, or insulin, the initial dose is 15 mg once daily, with the maximum recommended dosage not exceeding 30 mg once daily.

Child dose

There is no experience in children under 18 years of age, so its use is not recommended.

This medication may cause or worsen congestive heart failure in some patients, so symptoms and signs of heart failure should be carefully monitored at the start of treatment or after dosage increases. This medication should not be used in patients with heart failure or a history of heart failure, and if symptoms of heart failure occur, a doctor should be consulted immediately. This medication can cause fluid retention which may aggravate edema or heart failure, so healthcare personnel should be notified if symptoms of fluid retention appear. Patients with active bladder cancer or a history of bladder cancer should not take this medication, and if symptoms such as hematuria or urination difficulties occur, they should promptly inform a doctor. Patients with impaired liver function or severe kidney impairment should preferably avoid this medication and have regular liver function and kidney function tests. Women who are pregnant or may become pregnant should not take this medication, and women of childbearing potential should consider appropriate contraception while taking this medication as the risk of pregnancy may increase. Due to potential hypoglycemia, caution should be exercised for symptoms of hypoglycemia when used with insulin or other hypoglycemic agents, and dosages of other medications should be adjusted as necessary. Elderly patients or those with poor nutritional status or those engaging in vigorous exercise should use this medication cautiously, and regular monitoring for weight gain and edema is advised. During therapy, blood sugar, liver function, kidney function, and weight should be monitored regularly, and any adverse symptoms should be reported to healthcare personnel immediately. In case of an overdose, there may be no specific symptoms, but appropriate treatment should be received according to symptoms. Keep the medication out of reach of children and store it in its original container.

Serious side effects

Congestive heart failure, heart failure, severe edema, excessive and rapid weight changes, difficulty breathing, shortness of breath, hospitalization due to congestive heart failure, cardiovascular abnormalities, bladder cancer, liver abnormalities (liver failure, worsening liver disease, elevated ALT/AST), severe neurological symptoms (stroke, myocardial infarction), rash, severe allergic reactions, jaundice, urinary dysfunction, pain in the cornea and oral mucosa, severe skin reactions.

Mild side effects

• Upper respiratory tract infections
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that prevents light and air entry, avoiding humid places. It is best to store it at room temperature between 15 and 30 degrees Celsius, especially around 25 degrees Celsius.

Appearance

White or gray, round, biconvex tablet

Package unit

30 tablets/bottle