Expansemi Tablet

Adult dose

For children aged 12 and older and adults, an initial dosage of 4 tablets is recommended, with subsequent intervals of at least 6 hours. Do not exceed 16 tablets per day. Administer the lowest effective dose for the shortest duration possible, avoiding unnecessary long-term use. For the elderly, those aged 75 and older should have intervals of at least 6 hours. Patients with moderate renal impairment should have their administration intervals adjusted.

Child dose

For children aged 12 and older, the same dosage and intervals as for adults are applied.

This medication can strain the liver, so it is essential that individuals who frequently consume alcohol in amounts exceeding a certain limit consult a doctor or pharmacist before taking this medication. Severe rashes, blisters, or serious allergic reactions may occur during the use of this medication; if such symptoms appear, it should be discontinued immediately and a medical professional should be consulted. One of the components of this medication, tramadol, may induce seizures, so patients with a history of seizures or at high risk of seizures should exercise special caution and avoid taking it with other medications that increase the risk of seizures. Rarely, severe allergic reactions or anaphylaxis may occur during the use of this medication; if symptoms such as difficulty breathing, hives, or severe swelling arise, inform a medical professional immediately. In patients with severe respiratory diseases, there is an increased risk of respiratory depression when administering this medication, so it should be used cautiously in an environment equipped with medical equipment. This medication may cause respiratory depression or severe drowsiness/coma when taken with alcohol or certain sedatives, requiring careful consideration when used in conjunction with these substances. Patients with head injuries or brain diseases should be cautious when taking this medication, as it may exacerbate increased intracranial pressure or respiratory depression. This medication has the potential for psychological or physical dependence, and long-term use should be closely monitored for dependence. Patients with impaired liver function have a risk of liver damage when taking this medication, so they must strictly adhere to a doctor's instructions and avoid concurrent use with other acetaminophen-containing medications. Patients with specific genetic metabolic characteristics may experience excessive accumulation of the active ingredients in this medication, posing a serious risk of respiratory depression; a dosage adjustment or alternative medication may be necessary in such cases. This medication should not be administered to children under 12 years old or to adolescents under 18 years old who have undergone tonsillectomy or adenoidectomy, and special caution is advised for those aged 12 to 18 who may have additional risk factors. Patients with sleep apnea or hypoxemia may worsen after taking this medication; continuous monitoring of their condition is required, and dosage should be reduced or discontinued if necessary. This medication may cause hyponatremia; thus, symptoms should be closely monitored, especially in the elderly or those at risk of hyponatremia. Patients with certain allergies or conditions, severe respiratory depression, head injuries, those on specific medications, and pregnant or breastfeeding women should avoid using this medication. Drowsiness or dizziness may occur while driving or operating machinery due to this medication, so caution is advised after administration. In the case of overdose, severe respiratory depression, seizures, and liver damage may occur; it is vital to adhere to prescribed dosages and seek immediate medical attention in an emergency situation. This medication should be stored in a safe place out of reach of children and should not be shared with others.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confused consciousness, visual disturbances, paralysis, urination.

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air from entering and kept in a cool place below room temperature of 25 degrees Celsius.

Appearance

Pale yellow, rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle