Actorin Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once a day, regardless of meals. 1. Monotherapy This medication can be started at a dose of 15 mg once a day for patients whose blood sugar is not adequately controlled, and if the effect is insufficient, the dose can be increased to 30 mg once daily. 2. Combination therapy - Initial dose with sulfonylureas: 15 mg once a day - Initial dose with metformin: 15 mg once a day -

Child dose

There is no experience in children under 18 years, so administration is not recommended.

This medication is used to treat type 2 diabetes and helps control blood sugar by acting with insulin. This drug may place additional strain on the heart in some patients, potentially causing or worsening heart failure (congestive heart failure), so after starting treatment or increasing the dose, symptoms of heart failure such as weight change, shortness of breath, and swelling should be closely monitored. This medication should not be used in patients with heart failure, and if symptoms of heart failure occur, medical advice should be sought immediately to adjust the treatment. As this drug can cause fluid retention, which increases the risk of heart failure, patients with cardiovascular diseases like heart disease, hypertension, or myocardial infarction should take special caution. Patients with a history of or currently having bladder cancer should not be administered this drug, and if hematuria or urinary disorders occur during treatment, they should inform the physician immediately. Patients with impaired liver function or severe renal impairment should also preferably refrain from using this drug. Women who are pregnant or may become pregnant should not use this medication, and premenopausal women should use appropriate contraception as this drug can stimulate ovulation and raise the risk of pregnancy. During the use of this medication, regular monitoring of blood sugar and liver function tests should be conducted, and if symptoms such as weight gain, swelling, or shortness of breath occur, they should inform a physician immediately. Additionally, the risk of hypoglycemia may increase when this drug is used in conjunction with other diabetes medications or insulin, so when used together, patients should be well-informed about hypoglycemia symptoms and management methods. Elderly patients or those with impaired kidney or liver function should be monitored more closely during administration, and in case of overdose, immediate medical assistance should be sought for appropriate treatment. Finally, the safety and efficacy of this medication have not been confirmed in children, hence it is not used in that age group.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight change, dyspnea, edema), severe swelling (edema), breathing difficulty, liver issues (jaundice and liver failure), severe neurological symptoms (severe headache, seizures, altered consciousness, visual disturbances, paralysis), severe allergic reactions (hives), bladder cancer, worsening or hospitalization for heart failure, significant heart failure, hematuria, urinary disorders, urinary urgency, fatal and non-fatal

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that excludes light and air, avoiding humid places and kept at a temperature between 15 to 30 degrees Celsius. This helps maintain the efficacy of the medication and prevents degradation.

Appearance

White to grayish-white round tablet

Package unit

30 tablets/bottle, 90 tablets/bottle, 300 tablets/bottle