Liporactin Tablets 10 mg (Atorvastatin Calcium Trihydrate)

Adult dose

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily. For patients requiring more LDL-cholesterol reduction, it may start at 20 mg or 40 mg once daily. The dosing range is 10 to 80 mg once daily. Lipid levels should be analyzed 2 to 4 weeks after starting treatment to adjust the dosage. The treatment goal is to reduce LDL-cholesterol, thus it is recommended to evaluate treatment response using LDL-cholesterol levels. If LDL-cholesterol levels are unavailable, total cholesterol levels may be used to monitor treatment response. In patients with homozygous familial hypercholesterolemia, the dosing of this medication is 10 to 80 mg once daily and is given in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are unavailable.

Child dose

For pediatric patients (10 to 17 years) with heterozygous familial hypercholesterolemia, an initial recommended dose of 10 mg once daily is suggested, with a maximum dose of 20 mg once daily. The dosing should be adjusted based on treatment goals every 4 weeks.

This medication may cause muscle problems, so if symptoms such as muscle pain or weakness occur, it should be stopped immediately and consulted with a doctor. This medication should not be used in individuals with certain liver diseases, pregnant women, or children under 10 years of age. Individuals with poor liver function must consult a doctor before taking this medication and undergo regular liver function tests during use. It is advisable to avoid alcohol consumption while taking this medication, especially for those with a history of liver disease or alcohol addiction. This medication may interact with other drugs, so inform your doctor or pharmacist of any other medications you are taking. Particularly, caution is necessary when combined with certain antibiotics, antifungals, or HIV treatments, as the risk of muscle-related side effects may increase. Women of childbearing age should use appropriate contraceptive methods while taking this medication, and stop taking it immediately if pregnancy is confirmed. It is safer for breastfeeding women to avoid this medication, and if taking, breastfeeding should be discontinued. Caution is needed when administering this medication to children and the elderly, as particularly the elderly are at a higher risk for myopathy and should be closely monitored. If symptoms such as muscle pain, muscle weakness, fatigue, fever, etc., occur during use, notify a doctor immediately and undergo examination. There is no specific antidote for overdose, treatment will depend on symptoms, and liver function and muscle status should be regularly monitored. This medication should be stored in a cool place away from direct sunlight, out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe allergic reactions, severe skin adverse reactions, shortness of breath or respiratory difficulty, asthma attacks, respiratory issues accompanied by cough and fever, respiratory problems, yellowing of the skin or eyes (jaundice), profound lethargy, liver abnormalities (jaundice), sudden onset

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. Additionally, it is best stored at room temperature, avoiding extremely hot or cold places.

Appearance

White round film-coated tablets

Package unit

For domestic use (30 tablets) - 30 tablets/bottle, For domestic use (300 tablets) - 300 tablets/bottle