International Pioglitazone Tablet (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once a day regardless of meals. It can start at 15 mg once daily as monotherapy, and if effectiveness is insufficient, it can be increased up to 30 mg once daily. In combination therapy, the initial dose is also 15 mg once daily, and the maximum recommended dose should not exceed 30 mg once daily.

Child dose

There is no experience of use in children under 18 years, therefore administration is not recommended.

This medication is used for the treatment of type 2 diabetes, and blood sugar control effectiveness is achieved only in the presence of insulin. This medication can put strain on the heart, so it should not be used in patients with congestive heart failure, and symptoms of heart failure (such as rapid weight gain, shortness of breath, swelling, etc.) should be monitored carefully during treatment. Additionally, it can cause fluid retention, which may worsen symptoms of edema or heart failure, hence caution is required for patients with heart disease or impaired kidney function. While taking this medication, symptoms of hypoglycemia may occur, especially when taken alongside insulin or other hypoglycemics, so one should be prepared for the risk of hypoglycemia. This medication should not be administered to patients with bladder cancer or a history of bladder cancer, and if symptoms such as hematuria or urinary disturbances arise during treatment, the physician should be notified immediately. Patients with liver dysfunction should undergo regular liver function tests before and during the use of this medication, and if symptoms of liver damage (fatigue, loss of appetite, jaundice, etc.) appear, prompt medical attention should be sought. This medication may induce ovulation in premenopausal women, so effective contraception should be used if pregnancy is not desired. In elderly patients or those with diminished kidney function, caution is needed in the use of this medication, and regular monitoring is essential as weight gain and edema may occur. Finally, it is crucial to follow the physician's instructions when taking this medication and to consult immediately if any unusual symptoms arise during treatment.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight changes, shortness of breath, swelling), severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), liver abnormalities (jaundice, yellowing of skin or eyes, extreme lethargy), severe edema or urinary irregularities (decreased urine output, generalized swelling, high blood pressure), hospitalization due to hypoglycemia, severe skin reactions

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that can block light and air, and in a place free from moisture. The storage temperature should be between 15 to 30 degrees Celsius, and it is best to store it at around 25 degrees Celsius.

Appearance

White round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle