Donghwa Amlodipine Besilate Tablet 5 mg

Adult dose

Administer 5 mg orally once daily as amlodipine; can increase to a maximum of 10 mg daily depending on the patient’s response. Adjust according to age and symptoms.

It is very important that this medication is not used by certain patients. For instance, individuals who have had allergic reactions to this medication or similar drugs should avoid taking it. Additionally, breastfeeding women, patients with severe liver dysfunction, those with severe aortic stenosis, and patients in shock should not take this medication. Patients requiring caution include those with very low blood pressure, patients needing kidney dialysis, elderly individuals, and women who are pregnant or may become pregnant; they must use this medication cautiously. Pregnant women should particularly consult with their physician before taking this medication. This drug generally has good tolerability, but side effects such as flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea may occur during use. Rarely, various side effects like hypotension, vasculitis, neurological abnormalities, erectile dysfunction, skin rashes, and liver dysfunction have also been reported. Patients with weakened heart functions or liver dysfunction must exercise extra caution when taking this medication, and it can take time for blood pressure to gradually decrease after discontinuation; therefore, when using with other blood pressure medications, they should follow the guidance of a healthcare professional. This drug may not be suitable for the urgent treatment of heart conditions. This medication has the potential for drug interactions, particularly when taken with certain antibiotics, analgesics, blood pressure medications, and grapefruit juice. Taking it with grapefruit juice may amplify its effects and is not recommended. If pregnant or breastfeeding, the safety of this medication has not been established; it should only be used under the guidance of a physician when absolutely necessary, and breastfeeding should ideally be paused. This medication is only approved for use in children above a certain age, so it should not be used in children under 6 years old. In case of overdose, blood pressure may drop excessively and heart rate may increase rapidly, which may require emergency treatment. In such cases, patients should go to a hospital immediately for proper measures; gastric lavage or administration of activated charcoal may help reduce drug absorption. Finally, although this medication is known to have little effect on driving or operating machinery, caution is needed as individuals may experience dizziness.

Serious side effects

Hives, severe swelling (edema), angioedema, difficulty breathing, severe allergic reactions, severe skin reactions, toxic epidermal necrolysis, skin peeling, pain in oral/ocular mucosa, jaundice, liver abnormalities, hepatitis, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, severe neurological symptoms, markedly decreased urine output, severe systemic edema, elevated blood pressure, severe swelling or urination abnormalities, hematological abnormalities

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is advisable to store the medication at room temperature between 1 to 30 degrees Celsius, not in excessively hot or cold areas.

Appearance

White octagonal tablets

Package unit

30 tablets/bottle, 300 tablets/bottle