TDS besilate amlodipine tablet

Adult dose

5 mg orally once daily as amlodipine, which may be increased up to a maximum of 10 mg daily depending on the patient's response. Adjust according to age and symptoms.

This medication should not be used in certain patients. For example, individuals allergic to this drug or similar classes of drugs, breastfeeding women, individuals with severe liver dysfunction, those with severe aortic stenosis, and patients in a state of shock should not take this drug. Additionally, caution is required when using this medication. It should be used carefully in patients with very low blood pressure, those requiring renal dialysis, elderly patients, and women who are pregnant or may become pregnant. This drug has vasodilatory effects, which can lead to side effects such as flushing, fatigue, swelling, heart palpitations, dizziness, headache, drowsiness, abdominal pain, nausea, weakness, lethargy, pain, weight gain/loss, hypotension, vasculitis, increased tension, sensory loss/sensory abnormalities, peripheral neuropathy, fainting, taste disturbances, tremors, extrapyramidal disorders, erectile dysfunction, gynecomastia, changes in bowel habits, dry mouth, indigestion, gingival thickening, pancreatitis, vomiting, hyperglycemia, arthralgia, back pain, muscle cramps, muscle pain, leukopenia being reported. Patients with heart failure or liver dysfunction should be especially cautious when using this drug, and its effects appear slowly, making it unsuitable for acute angina treatment. This drug can interact with other medications, so it is advisable to consult a physician, especially if concomitantly taking grapefruit juice, certain antibiotics, antihypertensive agents, or immunosuppressants. Pregnant or breastfeeding women are advised not to use this medication as its safety has not been established except in special circumstances. In children, its efficacy has been confirmed for those over 6 years of age, but safety and efficacy have not been established for children under 6 years of age. In cases of overdose, severe hypotension and heart problems may occur, and immediate hospital treatment is necessary, where medical personnel should closely monitor blood pressure and heart condition and provide appropriate treatment. While the use of this drug is reported not to significantly affect the ability to drive or operate machinery, caution is needed as it may vary among individuals.

Serious side effects

• Hives
• toxic epidermal necrolysis
• skin peeling
• pain in oral/ocular mucous membranes
• chest tightness
• difficulty breathing
• severe swelling (edema)
• yellowing of the skin or eyes (jaundice)
• extreme fatigue
• sudden and very severe headache

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container as it may be sensitive to air or moisture. Additionally, avoid storing in excessively hot or cold places, and it is recommended to store it at room temperature between 1°C and 30°C.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle