Cobisc Tablet (Amlodipine Besylate)

Adult dose

Adults: Amlodipine is administered orally at a dose of 5 mg once a day, which may be increased to a maximum of 10 mg per day based on the patient's response. Adjustments should be made according to age and symptoms.

This medication should not be used in certain patients. For example, patients with allergies to this drug or other drugs in the same class, those who are breastfeeding, those with severe liver dysfunction, patients with severe aortic stenosis, and those in shock should avoid taking this medication. Additionally, patients with severe hypotension, those with kidney disease requiring dialysis, elderly individuals, pregnant women, or women who could become pregnant should use this medication cautiously. While taking this medication, various side effects may occur. The most common side effects include flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarer side effects may include dangerously low blood pressure, neurological symptoms, urination problems, liver function abnormalities, skin rashes, and allergic reactions. If any of these symptoms occur, consult a doctor immediately. This medication should be used cautiously in patients with heart failure, and dose adjustments may be necessary for patients with poor liver function. The effects of this medication appear slowly, so it is not suitable for the treatment of acute angina. This medication can interact with other drugs, so it is essential to inform your doctor or pharmacist of any other medications being taken. Particularly, taking it with grapefruit juice may enhance the blood pressure-lowering effect excessively, so it is advisable to avoid this combination. The safety of this medication has not been established in pregnant or breastfeeding women, so its use should be avoided where possible and used cautiously only when no alternatives are available. Children aged 6 years and older can use it, but the safety and effectiveness for children under 6 years have not been established. In case of overdose, dangerously low blood pressure and irregular heartbeats may occur, requiring immediate emergency treatment. This medication is not removed by dialysis, so specialized treatment is needed for overdoses. Finally, during the use of this medication, it is known that driving or operating machinery is not significantly affected.

Serious side effects

Hives, severe swelling (angioedema), hepatitis, jaundice, toxic epidermal necrolysis, severe allergic reactions, severe skin reactions, difficulty breathing, respiratory distress, severe swelling or urination problems accompanied by high blood pressure, pulmonary edema, severe hypotension, severe headache

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication is sensitive to light, so it must be stored in a sealed container that is not exposed to light. Furthermore, it is important to store it at a temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle