Rabeprazole Sodium Tablet 10 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: Typically, 10 mg should be taken orally once daily. Depending on symptoms, 20 mg can be taken orally once daily. Normally, it is administered for up to 8 weeks for gastric ulcer and up to 6 weeks for duodenal ulcer. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily for 4 to 8 weeks. If not treated, an additional 8 weeks of 10 mg or 20 mg twice daily can be administered.

This drug may not be appropriate for certain patients. First, it should not be administered to patients who are allergic or sensitive to this drug or its components. Patients allergic to penicillin-based or macrolide antibiotics should also exercise caution. This drug should not be used in patients taking certain medications, such as terfenadine, cisapride, pimodivir, astemizole, atazanavir, and rilpivirine. Women who are pregnant or breastfeeding should not take this drug. Patients with liver function problems or elderly patients, and those who have previously experienced hypersensitivity to medications should use this drug cautiously. If any allergic symptoms such as skin rash, urticaria, or itching occur during treatment with this drug, it should be stopped immediately. Additionally, regular blood tests are recommended as changes in red or white blood cell counts may occur in blood tests. Liver function tests are also necessary, and if liver dysfunction is detected, the medication should be discontinued. It may affect the heart and blood vessels, potentially causing symptoms like high blood pressure, myocardial infarction, or palpitations. Gastrointestinal side effects may include diarrhea, constipation, abdominal pain, nausea, and vomiting. Psychoneurological symptoms may include headaches, insomnia, anxiety, and dizziness; in rare cases, confusion or memory loss has also been reported. Respiratory symptoms may include cough, shortness of breath, and asthma, with severe cases potentially leading to pneumonia, so if fever or respiratory distress occurs, immediate consultation with medical professionals is advised. Musculoskeletal symptoms may present as muscle pain or joint pain. Skin-related side effects may include rashes, itching, hair loss, and in severe cases, serious skin reactions such as toxic epidermal necrolysis or Stevens-Johnson syndrome may occur. Eye-related side effects may include cataracts, glaucoma, and vision changes. Urological symptoms may include proteinuria, cystitis, and dysuria, which require caution. This drug may increase the risk of osteoporosis-related fractures with long-term use, and low magnesium levels may occur, necessitating regular checks and management during long-term use. Moreover, since this drug strongly suppresses gastric acid secretion, the risk of gastrointestinal bacterial infections may slightly increase. Caution is necessary when driving or operating machinery as drowsiness may occur. This drug may interact with other medications, so it is crucial to consult a professional, especially when taking blood coagulation-affecting drugs or certain antibiotics and antivirals. Pregnant or nursing individuals should not use this drug, and elderly patients may be more susceptible to side effects due to decreased liver function, thus requiring caution. Safety in pediatric patients has not been established, so it is better not to use this drug. When taking this medication, it should be swallowed whole without chewing or breaking, and it should be stored out of reach of children. There is no specific antidote for overdose; however, appropriate treatment should be administered based on symptoms. It is crucial to consult medical professionals immediately if any abnormal symptoms occur while taking this medication.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, acute hepatitis, liver dysfunction, jaundice, severe neurological symptoms (severe headache, thunderclap headache, seizures, consciousness confusion, vision changes, paralysis), severe edema accompanied by increased blood pressure, low magnesium level, interstitial nephritis (possible renal failure), interstitial pneumonia, toxic epidermal necrolysis (Lyell syndrome), skin and mucous membrane syndrome (Stevens-Johnson syndrome)

Mild side effects

• Rash
• itching
• decrease in red blood cells
• decrease in white blood cells
• increase in white blood cells
• increase in eosinophils
• increase in neutrophils
• decrease in lymphocytes
• anemia
• petechiae

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is safe to store at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the drug's effectiveness and prevent deterioration.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (7 tablets/Alu-Alu X 4)