Piover 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally at a dose of 15 mg once daily, regardless of meals. It starts as monotherapy and may be increased to 30 mg once daily if adequate effect is not obtained. In combination therapy, it is also administered at 15 mg once daily and may be used with sulfonylureas, metformin, or insulin. The maximum recommended dose does not exceed 30 mg once daily.

Child dose

There is no experience using this medication in pediatric patients under 18 years of age, so it is not recommended for use.

This medication is used for the treatment of Type 2 diabetes and helps control blood sugar by improving insulin sensitivity. However, this drug may worsen or induce heart failure; therefore, patients with heart failure or a history of heart failure should not use it. After starting treatment, carefully monitor for symptoms of heart failure such as weight changes, shortness of breath, and edema. If these symptoms occur, consult a doctor immediately. This drug can cause fluid retention leading to edema; therefore, patients with existing edema or with heart disease should use it with extra caution. Moreover, this drug may increase the risk of bladder cancer, so patients with active bladder cancer or a history of bladder cancer should not take it. It may affect liver function, so regular liver function tests should be performed before and during treatment, and if signs of liver dysfunction appear, inform a doctor immediately. There is a risk of hypoglycemia when taken with other antidiabetic agents such as insulin or sulfonylureas; thus, symptoms of hypoglycemia should be monitored, and other drug dosages adjusted as needed. Women who are pregnant or may become pregnant are advised not to use this medication, and premenopausal women should use appropriate contraceptive methods as it may stimulate ovulation. Elderly patients and those with decreased kidney or liver function need to be especially cautious when using this medication, with regular monitoring required. In cases of overdose, there may not be any specific symptoms, but notify healthcare providers immediately and seek appropriate treatment. This medication has not been established for safety and efficacy in children, so it is not recommended for use. Finally, this medication should be taken strictly according to a doctor's prescription and direction, and the dosage should not be altered or discontinued arbitrarily.

Serious side effects

Severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweats, pallor), severe skin adverse reactions (severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever), liver issues (jaundice) (yellowing of skin or eyes, severe fatigue), severe neurological symptoms (sudden

Mild side effects

• Upper respiratory tract infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• diarrhea

This medication should be stored in a sealed container to prevent exposure to air or moisture. The recommended storage temperature is between 1 to 30 degrees Celsius.

Appearance

White to off-white, convex cylindrical tablets

Package unit

30 tablets/bottle, 100 tablets/bottle