Pioron Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once a day regardless of meals. As monotherapy, start with 15 mg once daily; if the effect is insufficient, can be increased to 30 mg once daily. When used in combination with sulfonylureas, metformin, or insulin, the initial dose is 15 mg once daily. The maximum recommended dosage does not exceed 30 mg once daily.

Child dose

There is no experience with use in children under 18 years of age, therefore administration is not recommended.

This medication is used in the treatment of type 2 diabetes and only lowers blood glucose when insulin is also present. When taking this medication, careful attention must be paid to heart function. It may worsen or newly induce heart failure, particularly congestive heart failure; therefore, patients with heart failure or a history of heart failure should not take this medication. During treatment, observe carefully for sudden weight gain, shortness of breath, and swelling of the legs as signs of heart failure, and report any such symptoms to a doctor immediately. Additionally, this medication may cause fluid retention leading to edema; if edema worsens, consult a physician. This medication should not be administered to patients with bladder cancer or a history of bladder cancer, and immediate medical attention should be sought if hematuria or urination disorders occur. Patients with poor liver function should also exercise caution when taking this medication and should undergo regular liver function tests before and during treatment. There is a risk of hypoglycemia with this medication, so when taken with insulin or other hypoglycemic agents, patients should be vigilant for symptoms of hypoglycemia, and dose adjustments of other medications may be necessary as needed. Pregnant women or those who may become pregnant should not take this medication, and premenopausal women should use adequate contraception as this medication may stimulate ovulation. Elderly patients or those with deteriorated kidney function should be closely monitored while taking this medication. If symptoms such as sudden weight gain, edema, shortness of breath, hematuria, and urination disorders occur during treatment, consult medical personnel immediately. Finally, this medication should be taken once daily, and if a dose is missed, caution should be exercised to avoid taking double the dose the next day.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight changes, difficulty breathing, swelling), severe allergic reactions (hives), severe edema or urination abnormalities (visible hematuria, urination disorders, urgency), liver abnormalities (fatigue, loss of appetite, discomfort in the upper right abdomen, dark urine, jaundice, elevated ALT, liver failure), serious neurological symptoms (stroke), breathing problems (dyspnea), severe skin reaction (serious)

Mild side effects

• Headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal distension
• weight gain
• upper respiratory infection
• urinary tract infection
• hypoglycemia
• back pain

This medication should be stored in a container that blocks light and allows for airflow. Avoid humid areas, and it is best to store it in a cool place at a temperature between 15 to 30 degrees Celsius, particularly around 25 degrees Celsius.

Appearance

A round, convex tablet that is white to grayish-white in color.

Package unit

30 tablets, 300 tablets