Pigli 15 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once daily irrespective of meals. For patients who do not have adequate blood sugar control with monotherapy, treatment may be started at 15 mg orally once daily. If sufficient effect is not achieved, the dose may be increased to 30 mg once daily. For combination therapy, this medication is administered in conjunction with sulfonylureas, metformin, or insulin, all starting at 15 mg orally once daily. The maximum recommended dose is 30 mg once daily.

Child dose

There is no experience in patients under 18 years of age, therefore use is not recommended.

This medication is used for the treatment of diabetes and is effective only when insulin is present to lower blood sugar levels. This medication may worsen heart failure, therefore it should not be used in patients with heart failure or a history of heart failure. During treatment, fluid retention may occur, leading to symptoms such as edema, rapid weight gain, or difficulty breathing, which should be carefully monitored, and any such symptoms should be reported to a physician immediately. Patients with active bladder cancer or a history of bladder cancer should not take this medication. Caution is needed in patients with impaired liver function or severe kidney impairment, and regular liver and kidney function tests should be performed. As this medication poses a risk of hypoglycemia, those taking it with insulin or other hypoglycemic agents should be cautious of hypoglycemic symptoms, and dose adjustments may be necessary for other medications if needed. Side effects such as edema, weight gain, headache, upper respiratory infection may occur, so any of these symptoms should be reported to the attending physician. For premenopausal women, this medication may induce ovulation, increasing the likelihood of pregnancy, thus appropriate contraceptive methods should be used. It is recommended that women who are pregnant or may become pregnant do not take this medication, and that breastfeeding women consult a physician before taking it. This medication has not been studied in children and adolescents under 18 years of age, so its use is not recommended. Elderly patients should also use caution when taking this medication, especially those over 75 years old who should use it more cautiously. During the use of this medication, regular blood sugar and liver function tests should be performed, and any unusual symptoms should be reported to a physician immediately. There may not be specific symptoms associated with overdose, but appropriate treatment should be performed according to clinical symptoms. There may be drug interactions, so patients taking other medications must inform their physician or pharmacist. This medication should be kept out of reach of children and stored in its original container.

Serious side effects

Edema, severe swelling (edema), difficulty breathing, congestive heart failure, heart failure, cardiovascular abnormalities, bladder cancer, liver abnormalities (jaundice), liver failure, liver damage, severe allergic reactions (hives), stroke, myocardial infarction, brain stroke, seizures, severe neurological symptoms, severe edema or urinary disturbances, elevated blood pressure, severe swelling, jaundice, pneumonia, severe skin adverse reactions (severe rash, blisters, skin peeling, pain in oral/ocular mucosa)

Mild side effects

• Headache
• upper respiratory infection
• sinusitis
• myalgia
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius, avoiding excessively hot or cold areas.

Appearance

White to grayish-white, convex, cylindrical tablets

Package unit

30 tablets/bottle, 100 tablets/bottle