Limapran Tablets (Limaprost Alpha-Dex)

Adult dose

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger disease), the usual adult dosage is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal canal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dosage is 1 tablet orally 3 times daily. The dosage may be adjusted appropriately according to age and symptoms.

This medication should not be used by women who are pregnant or may become pregnant. This medication contains lactose, and should not be administered to patients with genetic disorders that prevent lactose digestion. Patients at risk of bleeding or taking anticoagulants should use this medication cautiously. Allergic reactions such as skin rashes or itching may occur during use; if such symptoms appear, medication should be discontinued immediately. Bleeding may occur infrequently, so if symptoms of bleeding appear, discontinue use and consult a doctor. Gastrointestinal issues such as diarrhea, nausea, abdominal pain, loss of appetite, and heartburn may occur. Regular liver function tests are advisable due to potential impacts on liver function that may lead to abnormal liver enzyme levels. Rarely, symptoms like tachycardia or hypotension and cyanosis of the extremities may occur. Various symptoms such as headache, facial flushing, dizziness, and warmth may appear, so careful observation of the body's condition is necessary. Patients with lumbar spinal canal stenosis should closely monitor symptom changes to decide whether to continue the medication; in severe cases, surgery may be required. Safety during pregnancy is not established, so if there is a possibility of pregnancy, this medication should be avoided, as uterine contractions have been reported in animal studies. Safety for children has not been confirmed, and there is limited experience in administration, so it is recommended not to administer to children. Elderly patients, whose physical functions may be weaker, should use this medication with caution, adjusting the dosage as necessary. High doses in healthy adults may temporarily lower blood pressure, so caution is required.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

Store this medication in a tightly closed container to prevent air or moisture from entering, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication.

Appearance

White round tablets

Package unit

84 tablets (21 tablets/PTP*4)