Exforge 5/80 mg (Amlodipine Besylate, Valsartan)

Adult dose

The recommended dose of this medication is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The dosages of 5/80 mg, 5/160 mg, and 10/160 mg should be adjusted according to blood pressure control status. Patients with renal or hepatic impairment need to be cautious regarding dosage adjustments or limits. Caution should be exercised when increasing the dose in patients aged 65 and over.

Child dose

Safety and efficacy for pediatric patients under 18 years of age have not been established, and the use of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to the ingredients of this medication, those who are pregnant or breastfeeding, patients with severe kidney or liver disease, and those with certain heart conditions should not take this medication. Patients with low sodium or fluid levels in their body may experience hypotension, so their status should be checked before taking the medication and monitored closely. Patients with high potassium levels should have their potassium levels checked frequently if taking this medication with other potassium-increasing drugs. Patients with kidney vascular issues or kidney transplant recipients should monitor kidney function closely when taking this medication. If symptoms of angioedema occur, discontinue the medication immediately and do not reuse it. Patients with heart failure or those recovering from a myocardial infarction should frequently check their kidney function and blood pressure while taking this medication, as there may be potential for worsening heart failure. Patients with acute myocardial infarction should be cautious as this medication may worsen angina or myocardial infarction symptoms. This medication may interact with other blood pressure-lowering medications, so it should be taken after consulting a physician. Dizziness or fatigue may occur when driving or operating machinery, so caution is advised. Overdose of this medication can lead to severe hypotension or shock, thus immediate medical attention is required. Safety for children or patients under 18 years of age has not been established, so it is not recommended for them. Elderly patients may be given the same dosage as adults, but their condition should be monitored closely. Women who are pregnant or planning to become pregnant should not take this medication, and nursing mothers are also advised to avoid it.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis

Mild side effects

• Headache
• dizziness
• drowsiness
• sensory disturbances
• lightheadedness
• tinnitus
• tachycardia
• palpitations
• syncope
• orthostatic hypotension

This medication should be stored in a tightly sealed container to protect against air and moisture. Storage temperature should be kept between 1 to 30 degrees Celsius at room temperature.

Appearance

Dark yellow round film-coated tablet

Package unit

28 tablets (14 tablets/PTP packaging x 2)