Clopidogrel 75 mg Tablet (Clopidogrel Bisulfate)

Adult dose

For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, Clopidogrel is orally administered at a dose of 75 mg once daily. For patients with acute coronary syndrome, start with a loading dose of 300 mg orally once on the first day, then maintain with 75 mg orally once daily. Aspirin 75-325 mg should be co-administered once daily during this time. For patients with atrial fibrillation, administer 75 mg orally once daily.

This medication is a drug that inhibits platelet aggregation to prevent the formation of blood clots. The effectiveness of this medication may be reduced in patients who do not produce sufficient active metabolites due to certain genetic factors, and in such cases, alternative treatment should be considered. Additionally, concomitant use of medications that activate CYP2C19 enzymes may increase drug concentration and the risk of bleeding, so co-administration should be avoided. This drug should not be used in patients with allergies to this medication, those with severe bleeding, severe liver damage, nursing women, and patients with genetic issues such as lactose intolerance. Caution should be exercised in patients with a high risk of bleeding, liver or kidney dysfunction, acute stroke, hypertension, elderly individuals, and underweight patients, and the medication should be discontinued in advance if surgery is planned. Since this drug may increase the risk of bleeding, notify healthcare professionals immediately if bleeding symptoms occur and get a blood test. Additionally, be careful as there may be an increased risk of bleeding when this medication is used together with other antiplatelet agents, anticoagulants, non-steroidal anti-inflammatory drugs, and selective serotonin reuptake inhibitors (SSRIs). During pregnancy, while the risk to the fetus is low, there may be an increased risk of bleeding during delivery, so discontinuation of the drug before delivery may be necessary. If breastfeeding, it is advisable to stop breastfeeding or discontinue the medication due to the possibility of the drug being secreted in breast milk. The safety and efficacy of this drug in children have not been established, and in elderly patients, the risk of side effects such as bleeding may be higher due to reduced physical function, thus requiring dosage adjustment and monitoring. In cases of overdose, bleeding time may be prolonged and bleeding complications may occur, so immediate medical attention is required for appropriate treatment. This drug should be stored out of reach of children and it is advisable not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough+fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Chest pain
• accidental injury
• influenza-like illness
• pain
• fatigue
• edema
• hypertension
• headache
• dizziness
• abdominal pain

This medication should be stored in a tightly closed container to protect it from air and moisture, maintaining a storage temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the drug's efficacy for a longer period.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle