Pigzone Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once daily regardless of meals. It can be started at a dose of 15 mg once daily as monotherapy, and if insufficiently effective, can be increased to 30 mg once daily. When used in combination with sulfonylureas, metformin, or insulin, the initial dose is 15 mg once daily. The maximum recommended dose does not exceed 30 mg once daily.

Child dose

There is no experience with use in children under 18 years of age, so it is not recommended.

This medication is used for the treatment of Type 2 Diabetes and helps improve insulin sensitivity to control blood sugar. However, it may affect heart function, so it should not be administered to patients with heart failure or a history of heart failure. During treatment, patients need to be closely monitored for symptoms of heart failure such as weight changes, dyspnea, and edema; if any of these symptoms occur, consultation with a physician should be sought immediately. Patients with active bladder cancer or a history of bladder cancer should not use this medication, and any occurrence of hematuria or urination difficulties during treatment should be reported to healthcare personnel immediately. Caution is also necessary for patients with impaired liver function or severe kidney disease. Furthermore, the risk of hypoglycemia may increase when this medication is used with insulin, so patients should be familiar with symptoms of hypoglycemia and may need adjustments in the dosage of concomitant medications. Women who are premenopausal may experience increased chances of ovulation due to this medication, so it is advisable to employ adequate contraceptive methods. Regular monitoring of blood sugar and liver function tests during treatment is essential, and patients should inform their physicians immediately if they experience sudden weight gain, edema, or shortness of breath. Elderly patients or those taking other oral hypoglycemic agents, as well as patients with heart conditions or renal dysfunction, should use this medication with particular caution. Lastly, it is safe not to administer this medication to pregnant women, women who may become pregnant, or breastfeeding mothers, and children under 18 years of age.

Serious side effects

Congestive heart failure, heart failure, severe edema, liver abnormalities (jaundice), bladder cancer, stroke, myocardial infarction, severe allergic reactions (including hives), hospitalization due to hypoglycemia, fatal and non-fatal liver failure due to hepatotoxicity, macular edema, severe neurological symptoms (seizures, confusion, visual disturbances, paralysis), asthma attacks, difficulty breathing, chest tightness, severe swelling (edema), cold sweat, pallor

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that blocks light and air, and care should be taken to avoid moisture. It is best to store it at a temperature between 15 and 30 degrees Celsius, especially at room temperature around 25 degrees Celsius.

Appearance

White to grayish-white, round, and convex tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle