Anaroksojeong (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2: Adult: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single-dose therapy, administer 60~120 mg orally. 2. For indication 3: Adult: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be administered twice a day, with a maximum of 180 mg per day. It is advisable to avoid taking it on an empty stomach.

This medication may cause gastrointestinal bleeding if taken by people who regularly consume more than three glasses of alcohol per day, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular diseases and may cause serious thrombotic reactions such as myocardial infarction or stroke, so patients with cardiovascular diseases or risk factors should be particularly careful. Serious adverse reactions affecting the gastrointestinal tract, such as gastrointestinal bleeding, ulcers, and perforations, may occur while taking this medication, so those with a history of gastrointestinal diseases or the elderly should be especially cautious and should inform medical personnel immediately if symptoms appear. This medication should not be used in specific patients, such as those with a history of peptic ulcers, severe blood disorders, serious liver or kidney diseases, severe heart failure, pregnant women in late pregnancy, and nursing mothers. Patients with a history of peptic ulcer, liver, kidney, or blood disorders, the elderly, and patients with hypertension should take this medication with caution and closely monitor for adverse reactions. This medication may cause allergic reactions, rashes, hives, or breathing difficulties; if these symptoms occur, immediate discontinuation and consultation with medical personnel is required. Long-term use may require regular liver function, kidney function, and blood tests to monitor for abnormalities, and if any signs are found, the administration should be stopped or adjusted. This medication may interact with other non-steroidal anti-inflammatory drugs, anticoagulants, diuretics, lithium, and methotrexate, so if there are other medications being taken, this should be reported, and caution is advised in combined use. During pregnancy, especially in the later stages, it may pose a risk to the fetus; hence, it should not be used. During the early or mid-pregnancy, it should only be administered at the minimum dosage under the judgment of a doctor. Safety for use in children has not been established, so caution is necessary, and the elderly are at higher risk for side effects, requiring more careful administration. This medication must be stored out of reach of children, and transferring it to another container is not advisable for quality maintenance.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing → severe allergic reactions. Shock, symptoms resembling anaphylaxis. Peptic ulcer, perforation, hematemesis, melena, blood in stool, shock → significant gastrointestinal adverse reactions. Symptoms and signs of gastrointestinal ulcers or bleeding. Symptoms of intestinal perforation. Thrombotic reactions in the cardiovascular system, myocardial infarction, stroke. Congestive heart failure. Liver dysfunction (including jaundice), fulminant hepatitis. Acute renal failure, nephrotic syndrome, liver.

Mild side effects

• Occasionally
• rashes
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea

This medication must be stored in a tightly sealed container to avoid exposure to air and moisture. Additionally, storing the medication at room temperature between 1°C and 30°C is the safest.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle