Fios Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once a day, regardless of meals. As monotherapy, it can be started at 15 mg once daily, and if the effect is insufficient, it may be increased to 30 mg once daily. In combination therapy, it is also administered at 15 mg once daily. The maximum recommended dose should not exceed 30 mg once daily.

Child dose

There is no experience in using this medication in children under 18 years; therefore, its use is not recommended.

This medication may cause or worsen heart failure in some patients, so changes in weight, breathing difficulties, edema, and other symptoms should be carefully monitored after administration. It should not be used in patients with heart failure or a history of heart failure. This medication may cause fluid retention when used with insulin; therefore, it should be used cautiously in patients at risk of heart failure. If blood in urine or urination disorders occur during treatment, there may be a possibility of bladder cancer, and you must notify your doctor immediately. It should not be administered to those with hypersensitivity to this medication or in patients with liver impairment, severe renal impairment, diabetic ketoacidosis, or Type 1 diabetes. Patients taking other oral hypoglycemic agents or those with edema, myocardial infarction, hypertensive heart diseases, or any heart conditions should use it with caution. Side effects may occur, including upper respiratory infections, headaches, edema, weight gain, and hypoglycemia, and particular attention should be paid to the potential occurrence of hypoglycemia and edema. If symptoms of abnormal liver function appear, immediate medical attention and necessary tests must be performed, and if liver enzyme levels significantly increase, administration should be discontinued. Pregnant women or those who may become pregnant should avoid using this medication, and premenopausal women should take adequate contraceptive measures to account for the increased risk of pregnancy. The safety and efficacy of this medication have not been established in children under 18 years of age, and caution should be exercised in elderly patients over 75 years of age. In cases of overdose, appropriate treatment should be administered based on symptoms, and it should be kept out of reach of children. This medication may interact with other drugs, so inform your doctor or pharmacist if you are taking any other medications. Regular monitoring of blood sugar and liver function tests is important throughout the treatment to check for abnormalities.

Serious side effects

Congestive heart failure, edema, increased blood pressure, bladder cancer, liver abnormalities (including jaundice), liver failure, stroke, myocardial infarction, heart failure, worsening of heart failure, symptoms and signs of heart failure (rapid weight gain, shortness of breath, etc.), significant heart failure, macular edema, severe allergic reactions (rash, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin reactions (severe rash with fever, blisters, skin peeling)

Mild side effects

• Upper respiratory infections
• headaches
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infections
• back pain

This medication may be sensitive to air or humidity; therefore, it should be stored in a sealed container. It is best to maintain an ambient temperature between 1 degree and 30 degrees Celsius.

Appearance

White round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle