Piorita Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once a day regardless of meals. For monotherapy, it starts at 15 mg once daily, and may be increased to 30 mg once daily if necessary. In combination therapy, 15 mg is administered once daily and can be combined with sulfonylurea, metformin, or insulin. The maximum recommended dose should not exceed 30 mg once daily.

Child dose

Experience is lacking for children under 18 years, so administration is not recommended.

This medication can affect heart function and should not be used in patients with heart failure. Symptoms of heart failure, such as sudden weight gain, shortness of breath, and swelling should be closely monitored after starting or increasing the dose. If such symptoms occur, the healthcare provider should be notified immediately, and the dose of this medication may need to be decreased or stopped. Additionally, this medication can cause fluid retention which may worsen heart failure, so patients with cardiovascular diseases should be especially cautious. Patients with active bladder cancer or a history of bladder cancer should not take this medication. Patients with liver disease or severe kidney disease should not use this medication, and if signs of liver dysfunction appear, a physician should be consulted immediately. Women who are pregnant or may become pregnant should not take this medication, and pre-menopausal women should use appropriate contraception as the risk of pregnancy may increase while taking this medication. This medication can increase the risk of hypoglycemia; therefore, when taken with insulin or other hypoglycemic agents, signs of hypoglycemia should be carefully monitored. Swelling or weight gain may occur, so if these symptoms arise, they should be reported to the healthcare provider, and regular monitoring of weight and swelling status is needed. Elderly patients should be especially cautious when taking this medication, and particular attention is required for those over 75 years of age. Regular blood sugar and liver function tests should be conducted during treatment, and if any abnormal symptoms occur, the physician should be consulted immediately. Overdose may not present special symptoms, but appropriate treatment should be received based on symptoms. Finally, this medication should not be used in children and adolescents under 18 years old as safety and efficacy have not been established.

Serious side effects

Congestive heart failure, heart failure, edema (including peripheral edema, generalized edema, and fluid retention), severe allergic reactions (hives, severe swelling), difficulty breathing, chest tightness, liver abnormalities (yellowing of the skin or eyes (jaundice), severe lethargy), serious neurological symptoms (sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis), significant decrease in urine output

Mild side effects

• Upper respiratory tract infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• urinary tract infection
• hypoglycemia
• back pain

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. The recommended storage temperature is between 1 degree and 30 degrees Celsius at room temperature.

Appearance

White circular tablet

Package unit

30 tablets/bottle