Ravestin Tablet 10 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: The usual adult dosage is 10 mg orally once daily as Rabeprazole Sodium. Depending on symptoms, 20 mg can be orally taken once daily. Treatment duration for gastric ulcers is up to 8 weeks and for duodenal ulcers up to 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms persist after an 8-week course of PPI, additional treatment may continue for another 8 weeks with 10 mg or 20 mg orally twice daily. However, the 20 mg twice daily dosage should only be considered for patients with confirmed severe mucosal injury. For symptom relief of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms are not controlled after 4 weeks, further medical attention is required. After symptom resolution, an on-demand therapy of 10 mg once daily can be used for any subsequent symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Depending on the patient, administer 10 mg or 20 mg orally once daily. For eradication of Helicobacter pylori: Patients with Helicobacter pylori infection should be treated with eradication therapy. It is recommended to co-administer this drug 20 mg, clarithromycin 500 mg, and amoxicillin 1 g twice daily for 7 days. For Zollinger-Ellison Syndrome: The recommended initial dosage for adults is 60 mg once daily. The dosage can be adjusted according to individual patient needs up to 120 mg daily. Doses up to 100 mg can be given once daily, while the 120 mg dose should be divided into 60 mg taken twice daily. Patients with Zollinger-Ellison syndrome have been treated with this drug for up to 1 year. ◯ In patients with liver dysfunction, adverse reactions related to hepatic encephalopathy have been reported in patients with cirrhosis. Therefore, it should be administered cautiously. ◯ In pediatric patients, safety has not been established. ◯ In elderly patients, caution is warranted as they often have decreased liver function.

This medication should not be given to patients who are allergic to certain components or have experienced hypersensitivity reactions. Patients allergic to penicillin or macrolide antibiotics should also not use this medication. Additionally, it is contraindicated for patients taking certain heart medications and for women who are pregnant or breastfeeding. Patients with impaired liver function or the elderly should be particularly cautious when using this product, and patients with a history of allergies should use it cautiously as well. If any allergic symptoms such as rash, urticaria, or itching occur during treatment, usage should be discontinued immediately. Regular blood tests are necessary as erythrocyte or leukocyte counts may change. Liver function may be affected, so periodic liver function tests are recommended. Rarely, symptoms related to the heart or gastrointestinal issues, as well as neurological symptoms, may occur. Adverse effects can occur in various areas including respiratory, musculoskeletal, skin, eyes, and urinary system, so any unusual symptoms should be reported to healthcare providers. Long-term use of this medication may increase the risk of bone fractures and lead to electrolyte imbalances such as hypomagnesemia, thus regular tests are necessary. Suppression of gastric acid secretion may slightly increase the risk of bacterial infections in the gastrointestinal tract, so if symptoms such as diarrhea persist, healthcare providers should be notified immediately. Caution should be exercised as drowsiness may occur when driving or operating machinery. This medication may interact with other drugs, so any concurrent medications must be reported to healthcare providers. Particularly careful attention is required when combined with antibiotics, antiviral medications, or drugs affecting blood coagulation. It should not be used during pregnancy or breastfeeding, and it should be given carefully to the elderly considering the potential for side effects due to decreased liver function. Safety has not been established for pediatric patients, so use is not recommended. In cases of overdose, there is no specific antidote available, thus treatment and supportive therapy should be symptom-based. This drug should be swallowed whole as a tablet and not chewed or crushed. Keep out of reach of children and avoid transferring to other containers. Long-term use of this medication may lead to vitamin B12 malabsorption, so periodic monitoring is necessary during prolonged use. This medication may trigger autoimmune diseases such as lupus erythematosus, so if related symptoms occur, it should be discontinued immediately and consultation with a specialist is required. Finally, during the use of this medication, if any unusual symptoms or discomfort are experienced, it is crucial to consult healthcare providers to receive appropriate action.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 to 30 degrees Celsius to ensure the efficacy of the medication is preserved and to use it safely.

Appearance

Pale yellow, round enteric-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu*2)