Losataplus F Tablets

Adult dose

The usual dose for this drug is 50 mg of Losartan Potassium/12.5 mg of Hydrochlorothiazide, administered once daily as 1 tablet. Doses exceeding 100 mg of Losartan Potassium/25 mg of Hydrochlorothiazide daily are not desirable. Patients who do not achieve adequate blood pressure control with monotherapy of Losartan or Hydrochlorothiazide should start with the combination therapy of Losartan Potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily.

Child dose

Due to insufficient experience in pediatric and adolescent use, the losartan-hydrochlorothiazide combination should not be administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients with a known allergy to this drug or its components, those with severely impaired kidney function, patients with specific electrolyte imbalances, or those with severe liver disease should not take this medication. Patients with very low blood pressure, those with issues in the renal vasculature, a history of liver disease, electrolyte disturbances, and elderly patients should use this medicine cautiously and should follow a physician's guidance. As this drug lowers blood pressure, dizziness or drowsiness may occur while taking it, hence caution is required when driving or operating machinery. Regular blood tests should be conducted to monitor kidney function and electrolyte status during treatment, and care should be taken to avoid excessively high or low potassium levels. This medication may interact with other drugs; hence patients taking potassium supplements, potassium-containing medications, diuretics, or antihypertensive agents should consult a doctor. The hydrochlorothiazide component can cause sensitivity to sunlight, increasing the risk of skin cancer; therefore, UV protection and monitoring of skin condition are important while taking this drug. Pregnant or nursing women should avoid using this drug, and those planning to become pregnant or who are pregnant must consult healthcare providers. This medication has insufficient experience in pediatric and adolescent use; hence it is considered safe to withhold from these populations. If any unusual symptoms or side effects occur during use, the patient should consult a doctor and follow their guidance.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme drowsiness, sudden and severe headache, lightning headache, seizures, altered consciousness, vision changes, paralysis, urinary changes

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory tract infection
• weakness/fatigue
• diarrhea

This medication should be stored in a dark container to protect it from light and kept in a tightly sealed container that allows little air penetration. It's important to maintain a room temperature between 1°C and 30°C.

Appearance

Light yellow oval film-coated tablet

Package unit

30 tablets per bottle