Medication info
Zarotan 50 mg Tablet (Losartan Potassium)

Zarotan 50 mg Tablet (Losartan Potassium)

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›50mg / 1 tablet
Manufacturer / importer
(주)서울제약
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200703082 · Notified 2007.03.14

Summary

Main use
Treatment of hypertension and kidney disease (in patients with type 2 diabetes)
Who takes it
Adults · Children
Adult dose
This medication can be taken without regard to meals, but it is recommended to take it at the same time each day. For hypertension treatment, the initial and maintenance dose is recommended as 50 mg orally once daily as losartan potassium. The maximum blood pressure-lowering effect is observed 3 to 6 weeks after initiation of therapy. If the therapeutic effect is insufficient, the dosage may be split into 2 doses per day or increased to a maximum of 100 mg once daily.
Child dose
For children and adolescents aged 6 years and older weighing between 20 kg and less than 50 kg, 25 mg is administered once daily, which can be adjusted to 50 mg once daily depending on the blood pressure response. For patients weighing over 50 kg:

Ingredients

Manufacturer
(주)서울제약

Efficacy & effects

Treatment of hypertension and kidney disease (in patients with type 2 diabetes)

  • Hypertension
  • kidney disease in patients with type 2 diabetes
View approved original text

This medication is used for the treatment of hypertension, especially helping in the treatment of kidney disease in patients with type 2 diabetes accompanied by hypertension. It stabilizes blood pressure and contributes to the protection of kidney function, thus effectively used for the treatment of hypertension and diabetes-related kidney complications.

How to take

Adult dose

This medication can be taken without regard to meals, but it is recommended to take it at the same time each day. For hypertension treatment, the initial and maintenance dose is recommended as 50 mg orally once daily as losartan potassium. The maximum blood pressure-lowering effect is observed 3 to 6 weeks after initiation of therapy. If the therapeutic effect is insufficient, the dosage may be split into 2 doses per day or increased to a maximum of 100 mg once daily.

Child dose

For children and adolescents aged 6 years and older weighing between 20 kg and less than 50 kg, 25 mg is administered once daily, which can be adjusted to 50 mg once daily depending on the blood pressure response. For patients weighing over 50 kg:

Precautions

This medication can cause serious harm or even death to the fetus when taken during pregnancy, especially in the second and third trimesters, so it should not be used by women who are pregnant or may become pregnant. It should not be administered to patients with severely impaired liver function, certain genetic disorders, or a history of angioedema. Special caution is required when administering this medication to the elderly, patients with impaired kidney function, patients with hyperkalemia, and patients with heart disease. During the course of this medication, side effects such as dizziness, muscle cramps, cough, and indigestion may occur; if symptoms are severe, consult a physician. Interactions may occur if this medication is taken with other antihypertensive drugs, potassium-sparing diuretics, or non-steroidal anti-inflammatory drugs, so it is crucial to inform healthcare providers of all current medications. Since this medication can pose risks to the fetus during pregnancy, it should be discontinued immediately if pregnancy is confirmed, and a physician should be consulted. Women who are breastfeeding should avoid using this medication if possible since it may be excreted in breast milk; if unavoidable, breastfeeding should be suspended. This medication should not be administered to children, especially those under the age of 6 or those with severely impaired kidney function. While taking this medication, blood pressure, kidney function, and electrolyte levels should be monitored regularly to check for abnormalities, especially in the elderly or those with kidney impairment. During treatment, sudden hypotension, loss of consciousness, and severe allergic reactions may occur, and if such symptoms are present, healthcare providers should be notified immediately. In case of overdose, hypotension and bradycardia may occur, so the dosage should be carefully adhered to and prompt treatment sought in case of abnormal symptoms. This medication should be stored out of reach of children, and caution should be exercised as transferring it to other containers may affect product quality.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema (which may cause airway obstruction due to swelling of the larynx/glottis, swelling of the face/lips/pharynx/tongue), chest tightness (including chest pain), difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, mucosal pain in oral or ocular regions, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory problems, skin

Mild side effects

  • Muscle cramps
  • back pain
  • leg pain
  • dizziness
  • congestion
  • upper respiratory infection
  • sinusitis
  • nausea
  • diarrhea
  • indigestion
Show 25 more
  • cough
  • sinus abnormalities
  • pharyngitis
  • myalgia
  • insomnia
  • headache
  • weakness/fatigue
  • edema/swelling
  • abdominal pain
  • chest pain
  • swelling of lips and eyelids
  • facial rash
  • skin peeling on palms
  • hemolysis
  • facial edema
  • fever
  • orthostatic effects
  • syncope
  • angina
  • second-degree atrioventricular block
  • hypotension
  • myocardial infarction
  • atrial fibrillation
  • palpitations
  • etc.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, it should be kept in a location that avoids extreme heat or cold, ideally at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.