Glezon Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once a day, regardless of meals. Starting dosage can be 15 mg once daily for monotherapy; if the effect is insufficient, it can be increased up to 30 mg once daily. For combination therapy, 15 mg is given once daily along with sulfonylureas, metformin, or insulin, and the maximum recommended dosage should not exceed 30 mg once daily.

Child dose

There is no experience in using this medication in children under 18 years of age, so its use is not recommended.

This drug is a medication that helps control blood sugar levels in patients with type 2 diabetes. It should not be used in patients with heart failure or a history of heart failure, as it may put a burden on the heart during administration. This drug can cause fluid retention, aggravating edema or heart failure, so if sudden weight gain or symptoms of heart failure such as shortness of breath occur, medical personnel should be notified immediately. Patients with active bladder cancer or a history of bladder cancer should also avoid this medication, and if symptoms such as hematuria or urinary disorders appear during treatment, they must report to a doctor immediately. Patients with poor liver function or severe renal impairment should avoid taking this medication, and it is advisable for women who are pregnant or may become pregnant not to use it. When used in combination with other diabetes medications, the risk of hypoglycemia may increase, so patients should be aware of hypoglycemia symptoms and management, and dosage adjustments of concomitant medications may be necessary. Regular blood sugar and liver function tests should be conducted while taking this medication, and if any abnormal symptoms such as sudden weight gain, edema, shortness of breath, or vision changes occur, immediate consultation with medical personnel is recommended. Additionally, premenopausal women should use appropriate contraception as this medication may stimulate ovulation, increasing the risk of pregnancy. Older adults or patients with impaired kidney function should use this medication cautiously, and in case of drug overdose, appropriate treatment should be sought immediately at a hospital. Finally, the safety and efficacy of this drug have not been established in children, therefore it is not used in pediatric patients.

Serious side effects

Edema, congestive heart failure, worsening of heart failure, cardiac adverse reactions, cardiovascular adverse events, liver abnormalities (liver failure, liver function impairment, elevated ALT, possibility of jaundice), bladder cancer, hypoglycemia (severe hypoglycemia), cardiovascular death, stroke, myocardial infarction, heart failure, macular edema, fractures, hospitalization due to edema, urticaria, severe allergic reactions, severe edema or urinary abnormalities, shortness of breath, severe skin adverse reactions

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• lower back pain

This medication should be stored in a container that protects it from light and air, and in a dry place. The recommended storage temperature is between 15 and 30 degrees Celsius, with 25 degrees Celsius being the most suitable.

Appearance

White to grayish round and convex tablets

Package unit

30 tablets/bottle