Raberit Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: In adults, the usual dose of Rabeprazole sodium is 10 mg orally once daily. Depending on symptoms, it may be taken as 20 mg orally once daily. Typically, it's given for up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If there is no treatment response after 8 weeks, further treatment for 8 weeks with 10 mg or 20 mg orally twice daily may be considered, but 20 mg twice daily is limited to patients with severe mucosal damage. For symptom relief in gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms remain unmanageable after 4 weeks, further medical evaluation is required. After symptoms have resolved, on-demand therapy with 10 mg once daily can be used to manage symptoms that occur later. For long-term maintenance therapy for gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily, depending on the patient. For Helicobacter pylori eradication: Patients with Helicobacter pylori infection should be treated with eradication therapy. It is recommended to administer this medication 20 mg in combination with Clarithromycin 500 mg and Amoxicillin 1 g, twice daily for 7 days. For Zollinger-Ellison syndrome: The recommended initial dose in adults is 60 mg once daily. The dosage can be adjusted up to 120 mg daily according to individual patient needs. Doses up to 100 mg can be given once daily, while 120 mg should be divided into two doses of 60 mg each. Patients with Zollinger-Ellison syndrome have experience with this medication for up to one year. 🏥 In patients with liver dysfunction, adverse effects of hepatic encephalopathy have been reported in cirrhotic patients. Therefore, it should be administered carefully. 🏥 In children, safety has not been established. 🏥 In the elderly, caution should be exercised as they often have impaired liver function.

Child dose

Safety in children has not been established.

This medication should not be taken by individuals allergic to certain components or with a history of hypersensitivity to benzimidazoles. Furthermore, caution is necessary for those allergic to penicillin or macrolide antibiotics, especially when used in combination during Helicobacter pylori eradication therapy. Patients taking Atazanavir or Rilpivirine or those who are pregnant or breastfeeding should not use this medication. This medication contains the pigment Yellow #5, so individuals allergic to this component should exercise caution. Additionally, patients with poor liver function, elderly individuals, and those with a history of drug allergies should use it carefully. During treatment, hypersensitivity reactions such as skin rash and itching can occur, so if such symptoms arise, discontinue use immediately. Blood tests may show abnormalities in red or white blood cell counts, liver function, therefore regular checks are recommended. Cardiac issues, blood pressure irregularities, and digestive symptoms (abdominal pain, diarrhea, nausea, etc.) may also occur, so medical consultation is advisable if symptoms arise. Nervous system side effects like headaches, dizziness, insomnia, as well as respiratory issues, muscle pain, and skin rashes have been reported, thus caution is warranted. If liver dysfunction, kidney issues, or severe allergic reactions are suspected, discontinue the medication immediately and visit a healthcare facility. This medication may increase the risk of bone fractures with long-term use, so regular check-ups are necessary during prolonged treatment. Additionally, as this medication suppresses gastric acid secretion, there may be a slight increase in the risk of gastrointestinal bacterial infections; if diarrhea persists, consult a doctor. This medication may cause drowsiness during driving or operating machinery, so caution is advised. There is potential for drug interactions, so when taking it with other medications, especially antibiotics, antivirals, and anticoagulants, it is essential to inform healthcare professionals. Pregnant or breastfeeding women should not use this medication, and caution is advised for the elderly due to the possibility of side effects from liver function decline. Safety in children has not been established, so it is best not to use it. In case of overdose, there is no specific antidote, so appropriate treatment should be administered according to symptoms, and the tablets should be swallowed whole without chewing or crushing.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, fever, interstitial pneumonia, abnormal lung sounds, fulminant hepatitis, liver dysfunction, jaundice, headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, agranulocytosis, hemolytic anemia, acute interstitial nephritis, thrombocytopenia, severe edema with increased blood pressure, severe allergic reactions, skin rash, blisters, skin peeling, pain in oral/ocular mucosa, severe

Mild side effects

Occasionally, rash, itching, hives, blood-related issues (anemia, leukopenia, leukocytosis, eosinophilia, neutrophilia, lymphocyte reduction, thrombocytopenia, hemolytic anemia), increased liver enzymes (ALT, AST, ALP, γ-GTP, LDH, total bilirubin), high blood pressure, myocardial infarction, abnormal electrocardiograms, migraine, syncope, and angina.

This medication should be stored in a tightly sealed container to prevent air or moisture. A storage temperature between 1 and 30 degrees Celsius at room temperature is recommended to maintain the medication's efficacy for a long time.

Appearance

Yellowish round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)