Rabephia Tablet 10 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Usually, 10 mg is administered orally once a day, and depending on symptoms, it can be increased to 20 mg once a day. Usually, treatment lasts up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks, and if not treated after 8 weeks, may continue with an additional 8 weeks of 10 mg or 20 mg. For symptom relief of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms do not improve after 4 weeks, additional consultation is needed. After symptoms have resolved, on-demand therapy with 10 mg once daily may be used to manage any recurrence of symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily, depending on the patient. For Helicobacter pylori eradication: Patients with Helicobacter pylori infection should be treated with eradication therapy. It is recommended to combine this drug (20 mg) with clarithromycin (500 mg) and amoxicillin (1 g), administered twice daily for 7 days. For Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dosage may be adjusted up to 120 mg per day based on individual patient needs. Doses of 100 mg can be administered once daily, while doses of 120 mg should be divided into 60 mg each twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to a year. Regarding patients with liver dysfunction: Adverse reactions of hepatic encephalopathy have been reported in patients with liver cirrhosis. Therefore, use should be done cautiously. Regarding children: Safety in pediatric patients has not been established. Regarding the elderly: Caution is advised in those with decreased liver function.

This medication should not be used in patients with specific allergic reactions. For example, it should not be administered to patients with hypersensitivity to this drug or its components, or to benzimidazole derivatives. Furthermore, patients allergic to specific antibiotics may experience issues when this medication is used in combination. It is safest for pregnant or breastfeeding women to avoid using this medication. In patients with impaired liver function or elderly patients, the side effects of the drug may be more severe; therefore, it should be used with caution. This medication may cause allergic reactions such as skin rash and itching; if such symptoms occur, use should be discontinued immediately. Regular blood tests or liver function tests should be performed, and appropriate action should be taken if abnormal findings are detected. It may affect various bodily systems including the heart, gastrointestinal, and nervous systems; immediate consultation with healthcare professionals is required if any symptoms arise. Long-term use of this medication may increase the risk of fractures, so caution is needed. Additionally, long-term use may lead to electrolyte imbalances such as hypomagnesemia, necessitating periodic testing. This medication suppresses gastric acid secretion, which may increase the risk of bacterial infections in the gastrointestinal tract; if symptoms like diarrhea persist, inform healthcare professionals immediately. Caution is needed while driving or operating machinery as drowsiness may occur. When taken with other medications, interactions may arise, so it is crucial to inform healthcare professionals of any concurrent medications being taken. There is no special antidote for overdose; appropriate treatment should be administered based on symptoms. This medication should be swallowed whole and not chewed or crushed. Keep out of reach of children and avoid transferring to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or breathing difficulty, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Rash
• hives
• itching
• decrease in red blood cells
• decrease in white blood cells
• increase in white blood cells
• increase in eosinophils
• increase in neutrophils
• decrease in lymphocytes
• anemia

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature to preserve the drug's efficacy for a longer duration.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets/box [14 tablets/Alu-Alu*2]