IYON Omeprazole Capsule

Adult dose

◎ Adults 1) Gastric ulcer: Administer 20mg of omeprazole orally once daily. Most ulcers may heal within 4 weeks, although healing time may vary among patients. If healing is not complete after the first 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medicines, administration of 40mg once daily generally results in healing within 8 weeks, although healing time may vary among patients. Repeat treatment if the ulcer recurs. 2) Short-term treatment of duodenal ulcer: Administer 20mg orally once daily. Most ulcers may heal within 2 weeks, although healing time may vary among patients. If healing is not complete after the first 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other medicines, administration of 40mg once daily generally results in healing within 4 weeks, although healing time may vary among patients. Repeat treatment if the ulcer recurs. 3) Treatment of reflux esophagitis and symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): - Reflux esophagitis: Administer 20mg orally once daily. Most cases may heal within 4 weeks, although healing time may vary among patients. If healing is not complete after the first 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medicines, administration of 40mg once daily generally results in healing within 8 weeks, although healing time may vary among patients. Repeat treatment if the condition recurs. - Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg orally once daily. Treatment for 2～4 weeks is generally sufficient for healing. 4) Maintenance treatment of severe reflux esophagitis and peptic ulcers that are difficult to treat: Administer 20mg orally once daily. If the condition recurs, the dose may be increased to 40mg once daily. 5) Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily. Continue treatment, adjusting the dose appropriately for each patient. More than 90% of patients respond to doses of 20 - 120mg per day. If administering more than 80mg per day, divide the daily dose into 2 doses. 6) Antibiotic combination therapy to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this medicine 20mg with amoxicillin 750 - 1000mg twice daily for 2 weeks. - Triple therapy: Administer this medicine 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the treatment effect is insufficient, omeprazole monotherapy may be continued. 7) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily. Most cases may heal within 4 weeks, although healing time may vary among patients. If healing is not complete after the first 4 weeks of treatment, continue treatment for an additional 4 weeks. 8) Maintenance prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID use in patients receiving long-term NSAID treatment with a history of gastric or duodenal lesions: Administer 20mg orally once daily. 9) Prevention of recurrence of reflux esophagitis: Administer 10mg orally once daily to prevent recurrence of reflux esophagitis. * Take this medicine whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This drug should not be used in patients with allergic reactions to its components. Caution should be exercised when administering it to patients with gastric ulcers suspected of being malignant, as symptom alleviation may delay diagnosis. It cannot be used in combination with certain antiviral agents, so patients on those medications must inform their healthcare provider. Patients with impaired liver function or the elderly should have their dosage adjusted or use this medication cautiously. Neurological symptoms such as headaches, dizziness, drowsiness might occur, and in severe cases, confusion or hallucinations may arise. Increases in liver enzyme levels or severe liver issues like hepatitis or liver failure may occur, so immediate consultation with a physician should be sought if unusual symptoms develop. Rarely, inflammation of the kidneys may occur, leading to kidney failure, so those with kidney function abnormalities should exercise caution. Gastrointestinal side effects such as diarrhea, nausea, and abdominal pain can commonly occur. Skin reactions such as rashes, itching, and in severe cases, serious skin reactions like Stevens-Johnson syndrome may occur, requiring discontinuation of the medication if skin abnormalities arise. Allergic reactions leading to angioedema or anaphylactic shock may rarely occur, necessitating immediate emergency measures. Blood cell counts may decrease, so if there are signs of bleeding or infection, the physician should be informed. Prolonged use may increase the risk of bone fractures, so caution is especially warranted in cases of high-dose administration or use for over one year. Long-term administration may lower blood magnesium levels, necessitating regular monitoring. There are many drug interactions, so it is essential to inform the doctor or pharmacist of any other medications being taken. Women who are pregnant or may become pregnant should use this drug cautiously as it may affect the fetus. If breastfeeding, it is best to avoid administering this drug; if unavoidable, breastfeeding should be discontinued. Safety in children has not been established, so its use is not recommended. Overdose may lead to symptoms such as vomiting, diarrhea, and headache, although most are temporary and serious consequences are rare. Keep out of reach of children, do not transfer to another container, and tightly close the container after use.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling faint, vertigo, confusion, excitability, aggression, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, flatulence, constipation, nausea, vomiting, abdominal pain, abdominal bloating, dry mouth, stomatitis, candidiasis of the gastrointestinal tract, erythema, rash, vesicular rash, hives, itching, dermatitis, vesiculobullous rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, fatigue, peripheral edema, increased sweating, blurred vision, visual impairment, taste disorder, breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, drug reactions with eosinophilia and systemic symptoms, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyp, hypocalcemia, hypokalemia

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, it is advised to keep it at room temperature between 1 to 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

A hard capsule with an upper reddish-brown and lower pink color, filled with white to grayish-white delayed-release granules.

Package unit

28 capsules/bottle, 100 capsules/bottle