Hiroxone Tablets (Hydrocortisone)

Adult dose

Hydrocortisone is administered orally at a dose of 10–120 mg daily, divided into 1 to 4 doses. Adjustments should be made based on age and symptoms.

This medication should not be used in patients with known allergies to this medication or its components. Caution is advised for patients with infections, especially in cases of infections unresponsive to antibiotics or systemic fungal infections, as these may worsen. It should not be administered to patients with viral infections such as herpes simplex, shingles, or chickenpox. This medication contains lactose and should not be used in patients with genetic issues such as lactose intolerance, lactose enzyme deficiency, or glucose-galactose malabsorption. Patients with specific diseases such as tuberculosis, keratitis, cataracts, hypertension, electrolyte disturbances, thrombosis, recent bowel anastomosis, peptic ulcers, psychosis, severe osteoporosis, glaucoma, acute myocardial infarction, etc., should be treated cautiously and only when necessary. Diabetic patients should regularly check their blood glucose and urine, as blood sugar levels may worsen. Caution is also needed for patients with renal failure, congestive heart failure, hypothyroidism, cirrhosis, fatty liver, myasthenia gravis, and the elderly. Long-term use of this medication may lead to adrenal insufficiency, increased risk of infections, hypertension, osteoporosis, vision changes, and other side effects, requiring regular check-ups and monitoring. This medication may interact with other drugs; therefore, it is essential to inform the healthcare provider of any medications currently being taken, particularly those affecting heart rhythm, anticoagulants, diuretics, antibiotics, or antiepileptics. Pregnant women or those who may become pregnant should consult a doctor before using this medication due to potential effects on the fetus, and nursing mothers are advised to discontinue breastfeeding. For children, the minimum effective dose should be given carefully due to the risk of growth retardation, and caution is also needed for potential side effects such as increased intracranial pressure with long-term administration. Elderly patients are at a higher risk of side effects such as infections, diabetes, osteoporosis, hypertension, cataracts, and glaucoma, and therefore require closer monitoring.

Serious side effects

Urticaria, severe swelling (edema) accompanied by raised blood pressure, difficulty breathing, chest tightness, cold sweats, pallor → severe allergic reaction, high fever accompanied by severe rash, blisters, skin exfoliation, oral/eye mucosal pain → severe skin adverse reactions, shortness of breath or respiratory distress, asthma attacks, respiratory problems combined with cough and fever, jaundice (yellowing of the skin or eyes), systemic fatigue →

Mild side effects

Diarrhea, nausea, vomiting, stomach pain, heartburn, abdominal bloating, ulcerative esophagitis, dry mouth, increased appetite, mental disorders, depression, euphoria, insomnia, headache, dizziness, seizures, increased intracranial pressure, osteoporosis, avascular necrosis of the femoral and humeral heads, myopathy, myalgia, arthralgia, spinal compression fractures, pathological fractures of the ilium, tendon rupture, nitrogen balance disturbance, fatty liver, edema, hypertension, potassium loss, hypokalemic alkalosis,

This medication is sensitive to light and should be stored in a tightly sealed container to block light. Additionally, it is advisable to keep the medication at room temperature between 1°C and 30°C. Proper storage can help maintain the medication's effectiveness for a longer period.

Appearance

White round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle