Pantazol 20 mg (Pantoprazole Sodium Sesquihydrate)

Adult dose

1. Treatment of mild gastroesophageal reflux disease and related symptoms Administer pantoprazole 20 mg orally once daily before breakfast. Symptom relief generally occurs within 2 ∼ 4 weeks, and healing may usually be achieved with 4 weeks of treatment. If healing is not achieved, an additional 4 weeks of treatment may result in healing. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis Administer pantoprazole 20 mg once daily before breakfast. If recurrence occurs, increase the dose to pantoprazole 40 mg daily, and after healing, reduce it again to 20 mg daily. 3. Prevention of gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs in patients requiring continuous treatment with nonsteroidal anti-inflammatory drugs Administer pantoprazole 20mg once daily. Dose adjustment is not required in elderly patients or patients with renal impairment. In patients with severe hepatic impairment, do not exceed 20 mg of this drug once daily.

This medication should not be used in certain patients. For example, individuals with an allergy to this medication or any of its components, or those who have experienced hypersensitivity reactions, should not take it. Additionally, patients currently taking certain antiviral medications such as atazanavir and nelfinavir should not use this medication. Women in early pregnancy or those who may become pregnant, as well as nursing mothers, are also advised against using this medication. Patients taking medications containing rilpivirine should not use this drug in conjunction. While taking this medication, various side effects may occur. Gastrointestinal symptoms such as abdominal pain, constipation, diarrhea, nausea, vomiting, and dry mouth are common. Systemic symptoms such as fatigue, lethargy, edema, and fever have also been reported. Liver function abnormalities may occur, so periodic monitoring of liver enzyme levels is necessary. Severe allergic reactions, skin rashes, hives, and serious skin disorders may occur infrequently, warranting caution. Additionally, symptoms such as muscle pain, joint pain, and neurological symptoms including headache, dizziness, and vision disturbances may occur. Mental health effects such as insomnia, depression, and hallucinations could also manifest. Various other adverse reactions including hematological abnormalities, metabolic issues, and kidney problems have been reported. This medication can mask malignant tumor symptoms or delay diagnosis; hence, if symptoms of gastric ulcers are present along with weight loss, recurrent vomiting, difficulty swallowing, hematemesis, or black stools, it is essential to confirm the malignancy. Regular check-ups during prolonged usage (especially for more than one year) are important. Patients with severe liver dysfunction may need to limit the daily dosage and undergo liver function tests during treatment. It is recommended not to use this medication for mild abdominal or intestinal pain. Long-term use of this medication may result in vitamin B12 absorption disorders, so caution is needed. Patients on continuous NSAID therapy may have an increased risk of gastrointestinal bleeding, necessitating careful administration. Additionally, prolonged high-dose use may increase the risk of hip, wrist, and spinal fractures. Cases of hypomagnesemia may occur rarely when used for more than three months and more frequently after one year of use. Hypomagnesemia can lead to severe arrhythmias or seizures, necessitating magnesium supplementation and discontinuation of the drug if needed. This medication suppresses gastric acid secretion, which can increase the number of bacteria in the stomach, raising the risk of infections such as salmonella, campylobacter, and Clostridium difficile. In particular, persistent diarrhea in hospitalized patients should raise suspicion of Clostridium infection. If dizziness or visual disturbances occur during use, activities requiring alertness such as driving or operating machinery should be avoided. This medication is metabolized by certain enzymes (CYP-450) in the liver and may interact with other drugs metabolized by the liver. In particular, bleeding risks may increase when taken with anticoagulants such as coumarins, necessitating frequent blood coagulation tests. Additionally, concurrent use with certain antiviral medications may reduce drug concentration and therapeutic efficacy. It should not be used during the first three months of pregnancy, and when used during pregnancy, it should only be used when its benefits outweigh the risks. Nursing mothers should avoid using this medication as it is excreted in breast milk. There is insufficient experience to recommend use in children under 12 years old. No specific symptoms of overdose are known, but if symptoms occur, symptomatic treatment should be provided. This medication should be taken whole and not chewed or crushed. The safety of long-term use is not fully established, so the benefits and risks should be carefully considered for use beyond one year. Keep this medication out of reach of children, and do not transfer it to other containers to maintain its quality.

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, epigastric pain, constipation, bloating, diarrhea, gastric polyp, nausea, vomiting, belching, dry mouth, fatigue, weakness, lethargy, swelling, elevated body temperature, fever, increased liver enzyme levels, elevated bilirubin, liver failure, arthralgia, myalgia, rhabdomyolysis, bone fracture, headache, dizziness, visual impairment, taste abnormalities, insomnia, sleep disturbances, depression, hallucinations, confusion, disorientation, interstitial nephritis, itching, skin redness, angioedema, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, photosensitivity, hyperglycemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia, gynecomastia, hyperlipidemia, lipid increase, weight change, hyponatremia, hypomagnesemia, elevated CK, anxiety, asthenia, back pain, bronchitis, chest pain, increased cough, indigestion, dyspnea, flu-like symptoms, gastroenteritis, gastrointestinal disturbances, tension, infection, migraine, cervical pain, pain, pharyngitis, rectal disturbances, rhinitis, elevated AST, sinusitis, upper respiratory infection, frequent urination, urinary tract infection, boil, allergic reaction, chills, abscess, facial swelling, generalized edema, warmth, hernia, abnormal clinical laboratory tests, malaise, moniliasis, tumor, nonspecific drug reaction, electrocardiogram abnormality, angina, arrhythmia, atrial fibrillation, coronary artery disease, congestive heart failure, bleeding, hypertension, hypotension, myocardial infarction, myocardial ischemia, palpitations, retinal vascular disease, syncope, tachycardia, phlebitis, thrombosis, vasodilation, decreased appetite, aphthous stomatitis, colitis, duodenitis, swallowing disorder, enteritis, esophageal bleeding, esophagitis, gastrointestinal tumor, gastrointestinal bleeding, gastrointestinal moniliasis, gingivitis, halitosis, hematemesis, increased appetite, melena, oral ulcer, oral moniliasis, periodontal abscess, periodontitis, rectal bleeding, gastric ulcer, bowel disturbances, tongue discoloration, ulcerative colitis, diabetes, goiter, gallbladder pain, hyperbilirubinemia, cholecystitis, cholelithiasis, jaundice, hepatitis, elevated ALP, anemia, petechiae, eosinophilia, iron deficiency anemia, leukocytosis, leukopenia, thrombocytopenia, dehydration, gout, thirst, weight gain, weight loss, arthritis, bone disease, joint disease, leg cramps, bursitis, tendinitis, abnormal dream, confusion, convulsions, dry mouth, speech impairment, hallucination, hyperactivity, decreased libido, anxiety, neuralgia, neuritis, neurological disorders, paresthesia, diminished reflex action, sleep disturbances, drowsiness, abnormal perception, tremors, asthma, epistaxis, hiccup, laryngitis, respiratory disorders, pneumonia, voice change, acne, alopecia, contact dermatitis, eczema, fungal dermatitis, bleeding, herpes simplex, herpes zoster, lichenoid dermatitis, papular rash, skin disease, skin ulcer, sweating, amblyopia, cataract, hearing loss, diplopia, otalgia, paralysis, glaucoma, otitis externa, taste abnormalities, tinnitus, albminuria, balanitis, mastalgia, cystitis, menstrual irregularities, urination disorders, epididymitis, hematuria, erectile dysfunction, kidney stones, renal pain, nocturia, prostate disorder, pyelonephritis, scrotal swelling, urethral pain, urethral disorder, urinary abnormalities, vaginitis, Clostridium difficile-associated diarrhea, hypocalcemia, hypokalemia, DRESS syndrome, microscopic colitis, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyp

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius for optimal efficacy.

Appearance

Yellow enteric-coated oval tablet.

Package unit

30 tablets/bottle