Amloem Tablets (formerly Novatin-M Tablets) (Amlodipine Mesilate Hydrate)

Adult dose

Adults: Administer amlodipine 5 mg orally once daily. If symptoms do not improve within 2 ∼ 4 weeks, the dose may be increased to a maximum of 10 mg per day according to the patient's response. Adjust the dose as appropriate according to symptoms.

This medication should not be used in certain patients. For example, those allergic to this drug or similar ingredients, women who are pregnant or may become pregnant, and women who are breastfeeding should avoid taking this medication. Additionally, patients with severely impaired cardiac function, those in a state of cardiac shock, patients with serious problems with cardiac valves, patients with unstable angina, those within one month after myocardial infarction, and patients with severe hepatic dysfunction or hypotension should not use this medication. Patients with severely impaired kidney function, elderly individuals, patients with acute heart failure, patients with very high blood pressure, patients with mild to moderate liver dysfunction, those with limited left ventricular function, patients with low cardiac reserve, and patients with diabetes should use this medication with extra caution. This medication is generally well-tolerated, but during use, side effects such as flushing, warmth, fatigue, swelling, palpitations, dizziness, headache, nausea, drowsiness, and ankle edema may occur. Additionally, rare side effects may include dry mouth, increased sweating, hypotension, fainting, neurological symptoms, gastrointestinal issues, skin rashes, abnormal liver function, and allergic reactions; if any abnormal symptoms appear, immediate consultation with healthcare professionals is necessary. Abruptly discontinuing this medication can worsen symptoms, so it should not be stopped arbitrarily without a doctor’s direction, and if dosage reduction is needed, it should be done gradually. Taking the medication with sufficient water is recommended, and since low blood pressure can cause dizziness or fatigue, caution is necessary when driving or operating dangerous machinery. This medication may interact with other blood pressure medicines or various drugs, so if other medications are being taken, it is essential to inform healthcare professionals. In particular, taking it with grapefruit juice may excessively enhance the blood pressure-lowering effect, so it is advisable to avoid this combination. Safety has not been established for use during pregnancy or breastfeeding, and if necessary, consultation with healthcare professionals should be conducted before making a decision. The safety and efficacy for pediatric patients have not been adequately confirmed, so it is preferable not to use this medication in children. Elderly patients may have slower drug metabolism, so starting with a lower dose and monitoring their condition closely is recommended. In the case of overdose, severe hypotension, headache, and cardiac abnormalities may occur, thus immediate medical attention should be sought.

Flushing with heat sensation, fatigue, edema, increased frequency of palpitations and angina, dizziness, headache, migraine, asthenia, abdominal pain, nausea, dyspepsia, drowsiness, ankle edema, dry mouth, increased sweating, weakness, lethargy, pain, weight gain, weight loss, chills, hypotension, orthostatic hypotension, orthostatic dizziness, peripheral ischemia, vasculitis, syncope, tachycardia, peripheral edema, hypertonia, sensory loss, sensory disturbances, peripheral neuropathy, taste disturbances, tremor, paralysis, erectile dysfunction, gynecomastia, changes in bowel habits, gastritis, gingival hypertrophy, pancreatitis, vomiting, fullness, loss of appetite, increased appetite, dysphagia, abdominal distension, hyperglycemia, thirst, increased serum cholesterol, elevated creatine kinase, arthralgia, low back pain, muscle cramps, myalgia, increased muscle tone, arthritis, single contraction, ataxia, back pain, leukopenia, thrombocytopenia, insomnia, mood changes, sexual dysfunction, abnormal dreams, depersonalization, apathy, anxiety, memory loss, sensitivity, depression, unease, confusion, fear, discomfort, cough, dyspnea, rhinitis, epistaxis, alopecia, purpura, skin discoloration, urticaria, photosensitivity reaction, rash, erythematous rash, papular rash, cold, moist skin, capillary dilation, rash, itching, angioedema, toxic epidermal necrolysis, tinnitus, visual disturbances, conjunctivitis, diplopia, eye pain, dry eyes, olfactory disturbance, taste disturbance, decreased vision, increased urinary frequency, urinary disorders, nocturia, polyuria, dysuria, hepatitis, jaundice, elevated liver enzyme levels, itching, rash, angioedema, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, myocardial infarction, arrhythmia, chest pain, hypotension, sinus node block, atrioventricular block, abdominal discomfort, precordial pain, diarrhea, loose stools, constipation, skin flushing, maculopapular rash, heaviness, heat sensation, impaired glucose tolerance, weakness, systemic hypotension, flushing, headache, reflex tachycardia, arrhythmia, shock state, unconsciousness, coma, non-cardiogenic pulmonary edema

This medication is sensitive to light, so it should be stored in a sealed container that blocks light. It is crucial to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White to grayish-white octagonal tablets

Package unit

300 tablets per bottle